CFTR Modulators: The Changing Face of Cystic Fibrosis in the Era of Precision Medicine

by Miquéias Lopes-Pacheco
Published 2020-02-01

CFTR modulators: Shedding light on precision medicine for cystic fibrosis

by Miquéias Lopes-Pacheco
Published 2016-09-01

Cell-Based Therapy for Silicosis

by Miquéias Lopes-Pacheco, Elga Bandeira, Marcelo M. Morales
Published 2016-01-01

Oxidative Stress-Derived Mitochondrial Dysfunction in Chronic Obstructive Pulmonary Disease: A Concise Review

by Mariana A. Antunes, Miquéias Lopes-Pacheco, Patricia R. M. Rocco
Published 2021-01-01

Combination of Correctors Rescues CFTR Transmembrane-Domain Mutants by Mitigating their Interactions with Proteostasis

by Miquéias Lopes-Pacheco, Clément Boinot, Inna Sabirzhanova, Daniele Rapino, Liudmila Cebotaru
Published 2017-04-01

Editorial: Emerging Therapeutic Approaches for Cystic Fibrosis

by Miquéias Lopes-Pacheco, Nicoletta Pedemonte, Anthony Kicic, Anthony Kicic, Anthony Kicic, Anthony Kicic
Published 2019-11-01

Rescue of NBD2 mutants N1303K and S1235R of CFTR by small-molecule correctors and transcomplementation.

by Daniele Rapino, Inna Sabirzhanova, Miquéias Lopes-Pacheco, Rahul Grover, William B Guggino, Liudmila Cebotaru
Published 2015-01-01

Moderate aerobic training improves cardiorespiratory parameters in elastase-induced emphysema

by Isabela Henriques, Miquéias Lopes-Pacheco, Miquéias Lopes-Pacheco, Gisele De Araujo Padilha, Patrícia S. Marques, Raquel F. Magalhães, Mariana A. Antunes, Marcelo Marcos Morales, Nazareth N. Rocha, Nazareth N. Rocha, Pedro Leme Silva, Debora Goncalves Xisto, Patricia Rieken Macedo Rocco
Published 2016-08-01

Mesenchymal Stromal Cell-Derived Extracellular Vesicles in Lung Diseases: Current Status and Perspectives

by Soraia C. Abreu, Soraia C. Abreu, Miquéias Lopes-Pacheco, Daniel J. Weiss, Patricia R. M. Rocco, Patricia R. M. Rocco
Published 2021-02-01

Repeated Administration of Bone Marrow-Derived Cells Prevents Disease Progression in Experimental Silicosis

by Miquéias Lopes-Pacheco, Debora G. Xisto, Felipe M. Ornellas, Mariana A. Antunes, Soraia C. Abreu, Patricia R.M. Rocco, Christina M. Takiya, Marcelo M. Morales
Published 2013-12-01

Impact of one versus two doses of mesenchymal stromal cells on lung and cardiovascular repair in experimental emphysema

by Hananda A. Poggio, Mariana A. Antunes, Nazareth N. Rocha, Jamil Z. Kitoko, Marcelo M. Morales, Priscilla C. Olsen, Miquéias Lopes-Pacheco, Fernanda F. Cruz, Patricia R. M. Rocco
Published 2018-11-01

Single Tyrosine Mutation in AAV8 Vector Capsid Enhances Gene Lung Delivery and Does Not Alter Lung Morphofunction in Mice

by Sabrina V. Martini, Adriana L. da Silva, Debora Ferreira, Karina Gomes, Felipe M. Ornellas, Miquéias Lopes-Pacheco, Emilia Zin, Hilda Petrs-Silva, Patricia R. M. Rocco, Marcelo M. Morales
Published 2014-08-01

Multiple doses of adipose tissue‐derived mesenchymal stromal cells induce immunosuppression in experimental asthma

by Ligia L. Castro, Jamil Z. Kitoko, Debora G. Xisto, Priscilla C. Olsen, Herbert L. M. Guedes, Marcelo M. Morales, Miquéias Lopes‐Pacheco, Fernanda F. Cruz, Patricia R. M. Rocco
Published 2020-02-01

Infusion of bone marrow mononuclear cells reduces lung fibrosis but not inflammation in the late stages of murine silicosis.

by Miquéias Lopes-Pacheco, Túlio G Ventura, Helena D'Anunciação de Oliveira, Leonardo C Monção-Ribeiro, Bianca Gutfilen, Sergio A L de Souza, Patrícia R M Rocco, Radovan Borojevic, Marcelo M Morales, Christina M Takiya
Published 2014-01-01

Mesenchymal Stromal Cells From Emphysematous Donors and Their Extracellular Vesicles Are Unable to Reverse Cardiorespiratory Dysfunction in Experimental Severe Emphysema

by Mariana A. Antunes, Mariana A. Antunes, Cassia L. Braga, Tainá B. Oliveira, Jamil Z. Kitoko, Jamil Z. Kitoko, Ligia L. Castro, Ligia L. Castro, Debora G. Xisto, Mariana S. Coelho, Nazareth Rocha, Nazareth Rocha, Rodrigo P. Silva-Aguiar, Celso Caruso-Neves, Eduarda G. Martins, Clara Fernandes Carvalho, Antônio Galina, Daniel J. Weiss, José R. Lapa e Silva, Miquéias Lopes-Pacheco, Miquéias Lopes-Pacheco, Fernanda F. Cruz, Fernanda F. Cruz, Patricia R. M. Rocco, Patricia R. M. Rocco
Published 2021-05-01

Therapeutic effects of bone marrow-derived mononuclear cells from healthy or silicotic donors on recipient silicosis mice

by Helena D’Anunciação de Oliveira, Elga Bernardo Bandeira de Melo, Johnatas Dutra Silva, Jamil Zola Kitoko, Bianca Gutfilen, Thiago Barboza, Sergio Augusto Lopes de Souza, Christina Maeda Takiya, Patricia Rieken Macedo Rocco, Miquéias Lopes-Pacheco, Marcelo Marcos Morales
Published 2017-11-01

Eicosapentaenoic Acid Enhances the Effects of Mesenchymal Stromal Cell Therapy in Experimental Allergic Asthma

by Soraia Carvalho Abreu, Soraia Carvalho Abreu, Miquéias Lopes-Pacheco, Miquéias Lopes-Pacheco, Adriana Lopes da Silva, Debora Gonçalves Xisto, Tainá Batista de Oliveira, Jamil Zola Kitoko, Jamil Zola Kitoko, Lígia Lins de Castro, Natália Recardo Amorim, Vanessa Martins, Luisa H. A. Silva, Cassiano Felippe Gonçalves-de-Albuquerque, Cassiano Felippe Gonçalves-de-Albuquerque, Hugo Caire de Castro Faria-Neto, Priscilla Christina Olsen, Daniel Jay Weiss, Marcelo Marcos Morales, Marcelo Marcos Morales, Bruno Lourenço Diaz, Patricia Rieken Macêdo Rocco, Patricia Rieken Macêdo Rocco
Published 2018-05-01

Dasatinib Reduces Lung Inflammation and Fibrosis in Acute Experimental Silicosis.

by Fernanda Ferreira Cruz, Lucas Felipe Bastos Horta, Lígia de Albuquerque Maia, Miquéias Lopes-Pacheco, André Benedito da Silva, Marcelo Marco Morales, Cassiano Felippe Gonçalves-de-Albuquerque, Christina Maeda Takiya, Hugo Caire de Castro-Faria-Neto, Patricia Rieken Macedo Rocco
Published 2016-01-01

Mesenchymal Stromal Cells Are More Effective Than Their Extracellular Vesicles at Reducing Lung Injury Regardless of Acute Respiratory Distress Syndrome Etiology

by Johnatas D. Silva, Ligia L. de Castro, Cassia L. Braga, Gisele P. Oliveira, Stefano A. Trivelin, Carlos M. Barbosa-Junior, Marcelo M. Morales, Claudia C. dos Santos, Daniel J. Weiss, Miquéias Lopes-Pacheco, Fernanda F. Cruz, Patricia R. M. Rocco
Published 2019-01-01

Eicosapentaenoic acid potentiates the therapeutic effects of adipose tissue-derived mesenchymal stromal cells on lung and distal organ injury in experimental sepsis

by Johnatas D. Silva, Miquéias Lopes-Pacheco, Ligia L. de Castro, Jamil Z. Kitoko, Stefano A. Trivelin, Natália R. Amorim, Vera L. Capelozzi, Marcelo M. Morales, Bianca Gutfilen, Sergio A. L. de Souza, Daniel J. Weiss, Bruno L. Diaz, Patricia R. M. Rocco
Published 2019-08-01