Inactivation of Sag/Rbx2/Roc2 E3 Ubiquitin Ligase Triggers Senescence and Inhibits Kras-Induced Immortalization

by Mingjia Tan, Hua Li, Yi Sun
Published 2015-01-01

The p21-dependent radiosensitization of human breast cancer cells by MLN4924, an investigational inhibitor of NEDD8 activating enzyme.

by Dong Yang, Mingjia Tan, Gongxian Wang, Yi Sun
Published 2012-01-01

Inactivation of SAG or ROC1 E3 Ligase Inhibits Growth and Survival of Renal Cell Carcinoma Cells: Effect of BIM

by Yu Wang, Mingjia Tan, Hua Li, Haomin Li, Yi Sun
Published 2019-06-01

Inactivation of SAG E3 ubiquitin ligase blocks embryonic stem cell differentiation and sensitizes leukemia cells to retinoid acid.

by Mingjia Tan, Yun Li, Ruiguo Yang, Ning Xi, Yi Sun
Published 2011-01-01

FBXW2 suppresses migration and invasion of lung cancer cells via promoting β-catenin ubiquitylation and degradation

by Fei Yang, Jie Xu, Hua Li, Mingjia Tan, Xiufang Xiong, Yi Sun
Published 2019-03-01

SAK, A New Polo-Like Kinase, Is Transcriptionally Repressed by p53 and Induces Apoptosis upon RNAi Silencing

by Jun Li, Mingjia Tan, Ling Li, Deepika Pamarthy, Theodore S. Lawrence, Yi Sun
Published 2005-04-01

Transgenic expression of Sag/Rbx2 E3 causes early stage tumor promotion, late stage cytogenesis and acinar loss in the Kras–PDAC model

by Qiang Zhang, Dongping Wei, Mingjia Tan, Haomin Li, Meredith A. Morgan, Yi Sun
Published 2020-06-01

Neddylation inhibitor MLN4924 suppresses cilia formation by modulating AKT1

by Hongmei Mao, Zaiming Tang, Hua Li, Bo Sun, Mingjia Tan, Shaohua Fan, Yuan Zhu, Yi Sun
Published 2019-03-01

SAG/ROC-SCFβ-TrCP E3 Ubiquitin Ligase Promotes Pro-Caspase-3 Degradation as a Mechanism of Apoptosis Protection

by Mingjia Tan, Jayme R. Gallegos, Qingyang Gu, Yuanhui Huang, Jun Li, Yetao Jin, Hua Lu, Yi Sun
Published 2006-12-01

Increased Piezo1 channel activity in interstitial Cajal-like cells induces bladder hyperactivity by functionally interacting with NCX1 in rats with cyclophosphamide-induced cystiti...

by Qian Liu, Bishao Sun, Jiang Zhao, Qingqing Wang, Fan An, Xiaoyan Hu, Zhenxing Yang, Jie Xu, Mingjia Tan, Longkun Li
Published 2018-05-01

The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor

by Jie Xu, Weihua Zhou, Fei Yang, Guoan Chen, Haomin Li, Yongchao Zhao, Pengyuan Liu, Hua Li, Mingjia Tan, Xiufang Xiong, Yi Sun
Published 2017-01-01

The FBXW7-SHOC2-Raptor Axis Controls the Cross-Talks between the RAS-ERK and mTORC1 Signaling Pathways

by Chuan-Ming Xie, Mingjia Tan, Xiao-Tong Lin, Di Wu, Yihan Jiang, Ye Tan, Haomin Li, Yuanyuan Ma, Xiufang Xiong, Yi Sun
Published 2019-03-01

Neddylation inactivation represses androgen receptor transcription and inhibits growth, survival and invasion of prostate cancer cells

by Xiaochen Zhou, Sumin Han, Kari Wilder-Romans, Grace Y. Sun, Hong Zhu, Xiaoqiang Liu, Mingjia Tan, Gongxian Wang, Felix Y. Feng, Yi Sun
Published 2020-04-01

SAG/RBX2 E3 Ubiquitin Ligase Differentially Regulates Inflammatory Responses of Myeloid Cell Subsets

by Xiufang Xiong, Xiufang Xiong, Nathan D. Mathewson, Nathan D. Mathewson, Nathan D. Mathewson, Hua Li, Mingjia Tan, Hideaki Fujiwara, Haomin Li, Pavan Reddy, Yi Sun, Yi Sun
Published 2018-12-01

MicroRNA-34a Attenuates Metastasis and Chemoresistance of Bladder Cancer Cells by Targeting the TCF1/LEF1 Axis

by Xiaobing Liu, Xin Liu, Yuqi Wu, Zhenqiang Fang, Qingjian Wu, Chao Wu, Yaxing Hao, Xia Yang, Jiang Zhao, Jia Li, Qingqing Wang, Zhenxing Yang, Jie Xu, Xiaoyan Hu, Mingjia Tan, Longkun Li
Published 2018-07-01