The beneficial effects of dietary restriction on learning are distinct from its effects on longevity and mediated by depletion of a neuroinhibitory metabolite.

by Mihir Vohra, George A Lemieux, Lin Lin, Kaveh Ashrafi
Published 2017-08-01

Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response.

by Victoria J Butler, Fuying Gao, Christian I Corrales, Wilian A Cortopassi, Benjamin Caballero, Mihir Vohra, Kaveh Ashrafi, Ana Maria Cuervo, Matthew P Jacobson, Giovanni Coppola, Aimee W Kao
Published 2019-08-01