Surviving the heat of the moment: a fungal pathogens perspective.

by Michelle D Leach, Leah E Cowen
Published 2013-03-01

Functional Divergence of Hsp90 Genetic Interactions in Biofilm and Planktonic Cellular States.

by Stephanie Diezmann, Michelle D Leach, Leah E Cowen
Published 2015-01-01

Lysine Deacetylases Hda1 and Rpd3 Regulate Hsp90 Function thereby Governing Fungal Drug Resistance

by Nicole Robbins, Michelle D. Leach, Leah E. Cowen
Published 2012-10-01

Modelling the regulation of thermal adaptation in Candida albicans, a major fungal pathogen of humans.

by Michelle D Leach, Katarzyna M Tyc, Alistair J P Brown, Edda Klipp
Published 2012-01-01

Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast.

by Michelle D Leach, Susan Budge, Louise Walker, Carol Munro, Leah E Cowen, Alistair J P Brown
Published 2012-12-01

Functional Genomic Screening Reveals Core Modulators of Echinocandin Stress Responses in Candida albicans

by Tavia Caplan, Elizabeth J. Polvi, Jinglin L. Xie, Shoshana Buckhalter, Michelle D. Leach, Nicole Robbins, Leah E. Cowen
Published 2018-05-01

Candida albicans Is Resistant to Polyglutamine Aggregation and Toxicity

by Michelle D. Leach, TaeHyung Kim, Sonja E. DiGregorio, Cathy Collins, Zhaolei Zhang, Martin L. Duennwald, Leah E. Cowen
Published 2017-01-01

Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues.

by Jinglin L Xie, Nora Grahl, Trevor Sless, Michelle D Leach, Sang Hu Kim, Deborah A Hogan, Nicole Robbins, Leah E Cowen
Published 2016-10-01

Ydj1 governs fungal morphogenesis and stress response, and facilitates mitochondrial protein import via Mas1 and Mas2

by Jinglin L. Xie, Iryna Bohovych, Erin O.Y. Wong, Jean-Philippe Lambert, Anne-Claude Gingras, Oleh Khalimonchuk, Leah E. Cowen, Michelle D. Leach
Published 2017-10-01

Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans

by Michelle D. Leach, Rhys A. Farrer, Kaeling Tan, Zhengqiang Miao, Louise A. Walker, Christina A. Cuomo, Robert T. Wheeler, Alistair J. P. Brown, Koon Ho Wong, Leah E. Cowen
Published 2016-05-01

The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation

by Jinglin L. Xie, Longguang Qin, Zhengqiang Miao, Ben T. Grys, Jacinto De La Cruz Diaz, Kenneth Ting, Jonathan R. Krieger, Jiefei Tong, Kaeling Tan, Michelle D. Leach, Troy Ketela, Michael F. Moran, Damian J. Krysan, Charles Boone, Brenda J. Andrews, Anna Selmecki, Koon Ho Wong, Nicole Robbins, Leah E. Cowen
Published 2017-09-01