Successful nilotinib therapy in a CML affected patient with A380T, P407S and V468A mutations, and a previous suboptimal cytogenetic response to imatinib

by Fabio Stagno, Alessandra Cupri, Stefania Stella, Michele Massimino, Silvia Rita Vitale, Paolo Vigneri
Published 2015-10-01

Insulin Receptor Isoforms Differently Regulate Cell Proliferation and Apoptosis in the Ligand-Occupied and Unoccupied State

by Michele Massimino, Laura Sciacca, Nunziatina Laura Parrinello, Nunzio Massimo Scalisi, Antonino Belfiore, Riccardo Vigneri, Paolo Vigneri
Published 2021-08-01

Knockout Serum Replacement Promotes Cell Survival by Preventing BIM from Inducing Mitochondrial Cytochrome C Release.

by Yuki Ishii, May Keu Nhiayi, Edison Tse, Jonathan Cheng, Michele Massimino, Donald L Durden, Paolo Vigneri, Jean Y J Wang
Published 2015-01-01

Non ABL-directed inhibitors as alternative treatment strategies for chronic myeloid leukemia

by Michele Massimino, Stefania Stella, Elena Tirrò, Chiara Romano, Maria Stella Pennisi, Adriana Puma, Livia Manzella, Antonino Zanghì, Fabio Stagno, Francesco Di Raimondo, Paolo Vigneri
Published 2018-02-01

Opportunities and Challenges of Liquid Biopsy in Thyroid Cancer

by Chiara Romano, Federica Martorana, Maria Stella Pennisi, Stefania Stella, Michele Massimino, Elena Tirrò, Silvia Rita Vitale, Sandra Di Gregorio, Adriana Puma, Cristina Tomarchio, Livia Manzella
Published 2021-07-01

Chk1 Inhibition Restores Inotuzumab Ozogamicin Citotoxicity in CD22-Positive Cells Expressing Mutant p53

by Elena Tirrò, Elena Tirrò, Michele Massimino, Michele Massimino, Chiara Romano, Chiara Romano, Maria Stella Pennisi, Maria Stella Pennisi, Stefania Stella, Stefania Stella, Silvia Rita Vitale, Silvia Rita Vitale, Annamaria Fidilio, Livia Manzella, Nunziatina Laura Parrinello, Fabio Stagno, Giuseppe Alberto Palumbo, Piera La Cava, Alessandra Romano, Francesco Di Raimondo, Francesco Di Raimondo, Paolo G. Vigneri, Paolo G. Vigneri
Published 2019-02-01

Impact of the Breakpoint Region on the Leukemogenic Potential and the TKI Responsiveness of Atypical BCR-ABL1 Transcripts

by Michele Massimino, Michele Massimino, Elena Tirrò, Elena Tirrò, Stefania Stella, Stefania Stella, Livia Manzella, Livia Manzella, Maria Stella Pennisi, Maria Stella Pennisi, Chiara Romano, Chiara Romano, Silvia Rita Vitale, Silvia Rita Vitale, Adriana Puma, Adriana Puma, Cristina Tomarchio, Cristina Tomarchio, Sandra Di Gregorio, Sandra Di Gregorio, Agostino Antolino, Francesco Di Raimondo, Francesco Di Raimondo, Paolo Vigneri, Paolo Vigneri
Published 2021-06-01

A Novel System for Semiautomatic Sample Processing in Chronic Myeloid Leukaemia: Increasing Throughput without Impacting on Molecular Monitoring at Time of SARS-CoV-2 Pandemic

by Stefania Stella, Silvia Rita Vitale, Michele Massimino, Adriana Puma, Cristina Tomarchio, Maria Stella Pennisi, Elena Tirrò, Chiara Romano, Federica Martorana, Fabio Stagno, Francesco Di Raimondo, Livia Manzella
Published 2021-08-01

Molecular Pathogenesis and Treatment Perspectives for Hypereosinophilia and Hypereosinophilic Syndromes

by Stefania Stella, Michele Massimino, Livia Manzella, Maria Stella Pennisi, Elena Tirrò, Chiara Romano, Silvia Rita Vitale, Adriana Puma, Cristina Tomarchio, Sandra Di Gregorio, Giuseppe Alberto Palumbo, Paolo Vigneri
Published 2021-01-01

Prognostic and Therapeutic Roles of the Insulin Growth Factor System in Glioblastoma

by Elena Tirrò, Elena Tirrò, Michele Massimino, Michele Massimino, Chiara Romano, Chiara Romano, Federica Martorana, Federica Martorana, Federica Martorana, Maria Stella Pennisi, Maria Stella Pennisi, Stefania Stella, Stefania Stella, Giuliana Pavone, Giuliana Pavone, Sandra Di Gregorio, Sandra Di Gregorio, Adriana Puma, Adriana Puma, Cristina Tomarchio, Cristina Tomarchio, Silvia Rita Vitale, Silvia Rita Vitale, Livia Manzella, Livia Manzella, Paolo Vigneri, Paolo Vigneri, Paolo Vigneri
Published 2021-02-01

Molecular Alterations in Thyroid Cancer: From Bench to Clinical Practice

by Elena Tirrò, Federica Martorana, Chiara Romano, Silvia Rita Vitale, Gianmarco Motta, Sandra Di Gregorio, Michele Massimino, Maria Stella Pennisi, Stefania Stella, Adriana Puma, Fiorenza Gianì, Marco Russo, Livia Manzella, Paolo Vigneri
Published 2019-09-01

Activation of the IGF Axis in Thyroid Cancer: Implications for Tumorigenesis and Treatment

by Livia Manzella, Michele Massimino, Stefania Stella, Elena Tirrò, Maria Stella Pennisi, Federica Martorana, Gianmarco Motta, Silvia Rita Vitale, Adriana Puma, Chiara Romano, Sandra Di Gregorio, Marco Russo, Pasqualino Malandrino, Paolo Vigneri
Published 2019-07-01

BCR-ABL1 Doubling-Times and Halving-Times May Predict CML Response to Tyrosine Kinase Inhibitors

by Maria Stella Pennisi, Maria Stella Pennisi, Stefania Stella, Stefania Stella, Silvia Rita Vitale, Silvia Rita Vitale, Adriana Puma, Adriana Puma, Sandra Di Gregorio, Sandra Di Gregorio, Chiara Romano, Chiara Romano, Elena Tirrò, Elena Tirrò, Michele Massimino, Michele Massimino, Agostino Antolino, Sergio Siragusa, Donato Mannina, Stefana Impera, Caterina Musolino, Giuseppe Mineo, Bruno Martino, Valentina Zammit, Francesco Di Raimondo, Francesco Di Raimondo, Livia Manzella, Livia Manzella, Fabio Stagno, Paolo Vigneri, Paolo Vigneri
Published 2019-08-01

Diagnostic Utility of the Immunohistochemical Expression of Serin and Arginine Rich Splicing Factor 1 (SRSF1) in the Differential Diagnosis of Adult Gliomas

by Giuseppe Broggi, Lucia Salvatorelli, Davide Barbagallo, Francesco Certo, Roberto Altieri, Elena Tirrò, Michele Massimino, Paolo Vigneri, Elia Guadagno, Grazia Maugeri, Velia D’Agata, Giuseppe Musumeci, Marco Ragusa, Giuseppe Maria Vincenzo Barbagallo, Daniela Russo, Rosario Caltabiano
Published 2021-04-01

Clinical Implications of Discordant Early Molecular Responses in CML Patients Treated with Imatinib

by Stefania Stella, Valentina Zammit, Silvia Rita Vitale, Maria Stella Pennisi, Michele Massimino, Elena Tirrò, Stefano Forte, Antonio Spitaleri, Agostino Antolino, Sergio Siracusa, Vincenzo Accurso, Donato Mannina, Stefana Impera, Caterina Musolino, Sabina Russo, Alessandra Malato, Giuseppe Mineo, Maurizio Musso, Ferdinando Porretto, Bruno Martino, Francesco Di Raimondo, Livia Manzella, Paolo Vigneri, Fabio Stagno
Published 2019-05-01