Basal Progenitors Contribute to Repair of the Prostate Epithelium Following Induced Luminal Anoikis

by Roxanne Toivanen, Adithi Mohan, Michael M. Shen
Published 2016-05-01

A computational systems approach identifies synergistic specification genes that facilitate lineage conversion to prostate tissue

by Flaminia Talos, Antonina Mitrofanova, Sarah K. Bergren, Andrea Califano, Michael M. Shen
Published 2017-04-01

Luminal Cells Are Favored as the Cell of Origin for Prostate Cancer

by Zhu A. Wang, Roxanne Toivanen, Sarah K. Bergren, Pierre Chambon, Michael M. Shen
Published 2014-09-01

Predicting Drug Response in Human Prostate Cancer from Preclinical Analysis of In Vivo Mouse Models

by Antonina Mitrofanova, Alvaro Aytes, Min Zou, Michael M. Shen, Cory Abate-Shen, Andrea Califano
Published 2015-09-01

Initiation of prostate cancer in mice by Tp53R270H: evidence for an alternative molecular progression

by Ruth L. Vinall, Jane Q. Chen, Neil E. Hubbard, Shola S. Sulaimon, Michael M. Shen, Ralph W. DeVere White, Alexander D. Borowsky
Published 2012-11-01

A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors

by Laura Crowley, Francesco Cambuli, Luis Aparicio, Maho Shibata, Brian D Robinson, Shouhong Xuan, Weiping Li, Hanina Hibshoosh, Massimo Loda, Raul Rabadan, Michael M Shen
Published 2020-09-01

Differential requirements of androgen receptor in luminal progenitors during prostate regeneration and tumor initiation

by Chee Wai Chua, Nusrat J Epsi, Eva Y Leung, Shouhong Xuan, Ming Lei, Bo I Li, Sarah K Bergren, Hanina Hibshoosh, Antonina Mitrofanova, Michael M Shen
Published 2018-01-01

NSD2 is a conserved driver of metastatic prostate cancer progression

by Alvaro Aytes, Arianna Giacobbe, Antonina Mitrofanova, Katia Ruggero, Joanna Cyrta, Juan Arriaga, Luis Palomero, Sonia Farran-Matas, Mark A. Rubin, Michael M. Shen, Andrea Califano, Cory Abate-Shen
Published 2018-12-01

Nestin+NG2+ Cells Form a Reserve Stem Cell Population in the Mouse Prostate

by Maher Hanoun, Anna Arnal-Estapé, Maria Maryanovich, Ali H. Zahalka, Sarah K. Bergren, Chee W. Chua, Avigdor Leftin, Patrik N. Brodin, Michael M. Shen, Chandan Guha, Paul S. Frenette
Published 2019-06-01

TGM4: an immunogenic prostate-restricted antigen

by Laura Crowley, Charles G Drake, Ran Reshef, Pawel Muranski, Aleksandar Obradovic, Timothy O’Donnell, Uri Laserson, Tiezheng Yuan, Emmanuel S Antonarakis, Zoila A Lopez-Bujanda, Thomas R Nirschl, Rodney Macedo, Alexandros Papachristodoulou, Jelani C Zarif, Mithil K Soni, Michael C Haffner, H Benjamin Larman, Michael M Shen
Published 2021-06-01