Helicobacter pylori-induced gastric pathology: insights from in vivo and ex vivo models

by Michael D. Burkitt, Carrie A. Duckworth, Jonathan M. Williams, D. Mark Pritchard
Published 2017-02-01

Long-Term Iron Deficiency and Dietary Iron Excess Exacerbate Acute Dextran Sodium Sulphate-Induced Colitis and Are Associated with Significant Dysbiosis

by Awad Mahalhal, Michael D. Burkitt, Carrie A. Duckworth, Georgina L. Hold, Barry J. Campbell, D. Mark Pritchard, Chris S. Probert
Published 2021-03-01

Oral Ferric Maltol Does Not Adversely Affect the Intestinal Microbiome of Patients or Mice, but Ferrous Sulphate Does

by Awad Mahalhal, Alessandra Frau, Michael D. Burkitt, Umer Z. Ijaz, Christopher A. Lamb, John C. Mansfield, Stephen Lewis, D. Mark Pritchard, Chris S. Probert
Published 2021-06-01

Oral iron exacerbates colitis and influences the intestinal microbiome.

by Awad Mahalhal, Jonathan M Williams, Sophie Johnson, Nicholas Ellaby, Carrie A Duckworth, Michael D Burkitt, Xuan Liu, Georgina L Hold, Barry J Campbell, D Mark Pritchard, Chris S Probert
Published 2018-01-01

Comparison of the human gastric microbiota in hypochlorhydric states arising as a result of Helicobacter pylori-induced atrophic gastritis, autoimmune atrophic gastritis and proton...

by Bryony N Parsons, Umer Z Ijaz, Rosalinda D'Amore, Michael D Burkitt, Richard Eccles, Luca Lenzi, Carrie A Duckworth, Andrew R Moore, Laszlo Tiszlavicz, Andrea Varro, Neil Hall, D Mark Pritchard
Published 2017-11-01

Inter-kingdom relationships in Crohn’s disease explored using a multi-omics approach

by Alessandra Frau, Umer Z. Ijaz, Rachael Slater, Daisy Jonkers, John Penders, Barry J. Campbell, John G. Kenny, Neil Hall, Luca Lenzi, Michael D. Burkitt, Marieke Pierik, Alistair C. Darby, Christopher S. J. Probert
Published 2021-01-01

A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharide

by Jonathan M. Williams, Carrie A. Duckworth, Alastair J. M. Watson, Mark R. Frey, Jennifer C. Miguel, Michael D. Burkitt, Robert Sutton, Kevin R. Hughes, Lindsay J. Hall, Jorge H. Caamaño, Barry J. Campbell, D. Mark Pritchard
Published 2013-11-01

Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine TumorsSummary

by Katie A. Lloyd, Bryony N. Parsons, Michael D. Burkitt, Andrew R. Moore, Stamatia Papoutsopoulou, Malcolm Boyce, Carrie A. Duckworth, Klaire Exarchou, Nathan Howes, Lucille Rainbow, Yongxiang Fang, Claus Oxvig, Steven Dodd, Andrea Varro, Neil Hall, D. Mark Pritchard
Published 2020-01-01

Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease

by Katie Lloyd, Stamatia Papoutsopoulou, Emily Smith, Philip Stegmaier, Francois Bergey, Lorna Morris, Madeleine Kittner, Hazel England, Dave Spiller, Mike H. R. White, Carrie A. Duckworth, Barry J. Campbell, Vladimir Poroikov, Vitor A. P. Martins dos Santos, Alexander Kel, Werner Muller, D. Mark Pritchard, Chris Probert, Michael D. Burkitt, The SysmedIBD Consortium
Published 2020-11-01

Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients

by Stamatia Papoutsopoulou, Stamatia Papoutsopoulou, Michael D. Burkitt, François Bergey, Hazel England, Rachael Hough, Lorraine Schmidt, David G. Spiller, Michael H. R. White, Pawel Paszek, Dean A. Jackson, Vitor A. P. Martins Dos Santos, Vitor A. P. Martins Dos Santos, Gernot Sellge, D. Mark Pritchard, Barry J. Campbell, Werner Müller, Chris S. Probert
Published 2019-09-01