Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN.

by Pradeep S Tanwar, LiHua Zhang, Tomoko Kaneko-Tarui, Michael D Curley, Makoto M Taketo, Poonam Rani, Drucilla J Roberts, Jose M Teixeira
Published 2011-01-01

Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model.

by Christopher K McCann, Whitfield B Growdon, Kashmira Kulkarni-Datar, Michael D Curley, Anne M Friel, Jennifer L Proctor, Hana Sheikh, Igor Deyneko, Jeanne A Ferguson, Vinod Vathipadiekal, Michael J Birrer, Darrell R Borger, Gayatry Mohapatra, Lawrence R Zukerberg, Rosemary Foster, John R Macdougall, Bo R Rueda
Published 2011-01-01