Gastrointestinal cell lines form polarized epithelia with an adherent mucus layer when cultured in semi-wet interfaces with mechanical stimulation.

by Nazanin Navabi, Michael A McGuckin, Sara K Lindén
Published 2013-01-01

Effect Of Interferon-γ and TNF-α on MUCl MUCIN Expression in Ovarian Carcinoma Cell Lines

by Sean Clark, Michael A. Mcguckin, Terry Hurst, Bruce G. Ward
Published 1994-01-01

Mucin dynamics in intestinal bacterial infection.

by Sara K Lindén, Timothy H J Florin, Michael A McGuckin
Published 2008-01-01

Serine protease(s) secreted by the nematode Trichuris muris degrade the mucus barrier.

by Sumaira Z Hasnain, Michael A McGuckin, Richard K Grencis, David J Thornton
Published 2012-01-01

Interleukin (IL)-22 from IL-20 Subfamily of Cytokines Induces Colonic Epithelial Cell Proliferation Predominantly through ERK1/2 Pathway

by Md. Moniruzzaman, Ran Wang, Varinder Jeet, Michael A. McGuckin, Sumaira Z. Hasnain
Published 2019-07-01

Influence of the MUC1 Cell Surface Mucin on Gastric Mucosal Gene Expression Profiles in Response to Helicobacter pylori Infection in Mice

by Yong H. Sheng, Garrett Z. Ng, Kim M. Summers, Alison L. Every, Gareth Price, Sumaira Z. Hasnain, Philip Sutton, Philip Sutton, Michael A. McGuckin, Michael A. McGuckin
Published 2020-07-01

Enterococcus faecalis AHG0090 is a Genetically Tractable Bacterium and Produces a Secreted Peptidic Bioactive that Suppresses Nuclear Factor Kappa B Activation in Human Gut Epithel...

by Páraic Ó Cuív, Rabina Giri, Emily C. Hoedt, Michael A. McGuckin, Jakob Begun, Mark Morrison
Published 2018-04-01

Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion.

by Sumaira Z Hasnain, Paul A Dawson, Rohan Lourie, Peter Hutson, Hui Tong, Richard K Grencis, Michael A McGuckin, David J Thornton
Published 2017-02-01

Fibre Intake Is Independently Associated with Increased Circulating Interleukin-22 in Individuals with Metabolic Syndrome

by Luciana Torquati, Jeff S. Coombes, Lydia Murray, Sumaira Z. Hasnain, Alistair R. Mallard, Michael A. McGuckin, Robert G. Fassett, Ilaria Croci, Joyce S. Ramos
Published 2019-04-01

MUC1 limits Helicobacter pylori infection both by steric hindrance and by acting as a releasable decoy.

by Sara K Lindén, Yong H Sheng, Alison L Every, Kim M Miles, Emma C Skoog, Timothy H J Florin, Philip Sutton, Michael A McGuckin
Published 2009-10-01

Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment.

by Ying Dong, Carson Stephens, Carina Walpole, Joakim E Swedberg, Glen M Boyle, Peter G Parsons, Michael A McGuckin, Jonathan M Harris, Judith A Clements
Published 2013-01-01

Gut microbiota shape the inflammatory response in mice with an epithelial defect

by Ran Wang, Md Moniruzzaman, Kuan Yau Wong, Percival Wiid, Alexa Harding, Rabina Giri, Wendy (Hui) Tong, Jackie Creagh, Jakob Begun, Michael A. McGuckin, Sumaira Z. Hasnain
Published 2021-01-01

GRP78 expression in tumor and perinephric adipose tissue is not an optimal risk stratification marker for clear cell renal cell carcinoma.

by Kunyu Shen, David A Vesey, Robert J Ellis, Sharon Juliet Del Vecchio, Yeoungjee Cho, Armando Teixeira-Pinto, Michael A McGuckin, David W Johnson, Glenda C Gobe
Published 2019-01-01

Adult non-cystic fibrosis bronchiectasis is characterised by airway luminal Th17 pathway activation.

by Alice C-H Chen, Megan L Martin, Rohan Lourie, Geraint B Rogers, Lucy D Burr, Sumaira Z Hasnain, Simon D Bowler, Michael A McGuckin, David J Serisier
Published 2015-01-01

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa.

by Lucy D Burr, Geraint B Rogers, Alice C-H Chen, Steven L Taylor, Simon D Bowler, Rebecca L Keating, Megan L Martin, Sumaira Z Hasnain, Michael A McGuckin
Published 2018-01-01

A Nucleotide Analog Prevents Colitis-Associated Cancer via Beta-Catenin Independently of Inflammation and AutophagySummary

by Yong Hua Sheng, Rabina Giri, Julie Davies, Veronika Schreiber, Saleh Alabbas, Ramya Movva, Yaowu He, Andy Wu, John Hooper, Brett McWhinney, Iulia Oancea, Gregor Kijanka, Sumaira Hasnain, Andrew J. Lucke, David P. Fairlie, Michael A. McGuckin, Timothy H. Florin, Jakob Begun
Published 2021-01-01

Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis.

by Chad K Heazlewood, Matthew C Cook, Rajaraman Eri, Gareth R Price, Sharyn B Tauro, Douglas Taupin, David J Thornton, Chin Wen Png, Tanya L Crockford, Richard J Cornall, Rachel Adams, Masato Kato, Keats A Nelms, Nancy A Hong, Timothy H J Florin, Christopher C Goodnow, Michael A McGuckin
Published 2008-03-01