CRISPR/Cas9-Mediated Specific Integration of <i>Fat-1</i> and <i>IGF-1</i> at the p<i>Rosa26</i> Locus

by Wenni You, Mengjing Li, Yilin Qi, Yanbing Wang, Yiwu Chen, Ying Liu, Li Li, Hongsheng Ouyang, Daxin Pang
Published 2021-07-01

The Possible Role of Complete Loss of Myostatin in Limiting Excessive Proliferation of Muscle Cells (C2C12) via Activation of MicroRNAs

by Peixuan Huang, Daxin Pang, Kankan Wang, Aishi Xu, Chaogang Yao, Mengjing Li, Wenni You, Qiushuang Wang, Hao Yu
Published 2019-02-01

Efficient Generation of Orthologous Point Mutations in Pigs via CRISPR-assisted ssODN-mediated Homology-directed Repair

by Kankan Wang, Xiaochun Tang, Yan Liu, Zicong Xie, Xiaodong Zou, Mengjing Li, Hongming Yuan, Hongsheng Ouyang, Huping Jiao, Daxin Pang
Published 2016-01-01

CRISPR/Cas9-Mediated Hitchhike Expression of Functional shRNAs at the Porcine <i>miR-17-92</i> Cluster

by Chao Lu, Daxin Pang, Mengjing Li, Hongming Yuan, Tingting Yu, Peixuan Huang, Jianing Li, Xue Chen, Huping Jiao, Zicong Xie, Hongsheng Ouyang
Published 2019-02-01

HMEJ-mediated site-specific integration of a myostatin inhibitor increases skeletal muscle mass in porcine

by Mengjing Li, Xiaochun Tang, Wenni You, Yanbing Wang, Yiwu Chen, Ying Liu, Hongming Yuan, Chuang Gao, Xue Chen, Zhiwei Xiao, Hongsheng Ouyang, Daxin Pang
Published 2021-12-01

Site-Specific Fat-1 Knock-In Enables Significant Decrease of n-6PUFAs/n-3PUFAs Ratio in Pigs

by Mengjing Li, Hongsheng Ouyang, Hongming Yuan, Jianing Li, Zicong Xie, Kankan Wang, Tingting Yu, Minghao Liu, Xue Chen, Xiaochun Tang, Huping Jiao, Daxin Pang
Published 2018-05-01

Optimization of a CRISPR/Cas9-mediated Knock-in Strategy at the Porcine Rosa26 Locus in Porcine Foetal Fibroblasts

by Zicong Xie, Daxin Pang, Kankan Wang, Mengjing Li, Nannan Guo, Hongming Yuan, Jianing Li, Xiaodong Zou, Huping Jiao, Hongsheng Ouyang, Zhanjun Li, Xiaochun Tang
Published 2017-06-01

CD36 deficiency ameliorates drug-induced acute liver injury in mice

by Chen Zhang, Xiao Shi, Zhongping Su, Chao Hu, Xianmin Mu, Jinshun Pan, Mengjing Li, Fengmeng Teng, Tao Ling, Ting Zhao, Che Xu, Guozhong Ji, Qiang You
Published 2021-06-01

The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double-strand break repair

by Tao Huang, Shenli Yuan, Lei Gao, Mengjing Li, Xiaochen Yu, Jianhong Zhan, Yingying Yin, Chao Liu, Chuanxin Zhang, Gang Lu, Wei Li, Jiang Liu, Zi-Jiang Chen, Hongbin Liu
Published 2020-05-01

Lysine-222 succinylation reduces lysosomal degradation of lactate dehydrogenase a and is increased in gastric cancer

by Xiang Li, Chen Zhang, Ting Zhao, Zhongping Su, Mengjing Li, Jiancheng Hu, Jianfei Wen, Jiajia Shen, Chao Wang, Jinshun Pan, Xianmin Mu, Tao Ling, Yingchang Li, Hao Wen, Xiaoren Zhang, Qiang You
Published 2020-08-01

Genetically modified pigs are protected from classical swine fever virus.

by Zicong Xie, Daxin Pang, Hongming Yuan, Huping Jiao, Chao Lu, Kankan Wang, Qiangbing Yang, Mengjing Li, Xue Chen, Tingting Yu, Xinrong Chen, Zhen Dai, Yani Peng, Xiaochun Tang, Zhanjun Li, Tiedong Wang, Huancheng Guo, Li Li, Changchun Tu, Liangxue Lai, Hongsheng Ouyang
Published 2018-12-01