Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations

by Lulu Huang, Audrey Low, Sagar S. Damle, Melissa M. Keenan, Steven Kuntz, Susan F. Murray, Brett P. Monia, Shuling Guo
Published 2018-01-01

Comprehensive profiling of amino acid response uncovers unique methionine-deprived response dependent on intact creatine biosynthesis.

by Xiaohu Tang, Melissa M Keenan, Jianli Wu, Chih-An Lin, Laura Dubois, J Will Thompson, Stephen J Freedland, Susan K Murphy, Jen-Tsan Chi
Published 2015-04-01

Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis.

by Jacob L Mercer, Joseph P Argus, Donna M Crabtree, Melissa M Keenan, Moses Q Wilks, Jen-Tsan Ashley Chi, Steven J Bensinger, Catherine P Lavau, Daniel S Wechsler
Published 2015-01-01

ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate.

by Melissa M Keenan, Beiyu Liu, Xiaohu Tang, Jianli Wu, Derek Cyr, Robert D Stevens, Olga Ilkayeva, Zhiqing Huang, Laura A Tollini, Susan K Murphy, Joseph Lucas, Deborah M Muoio, So Young Kim, Jen-Tsan Chi
Published 2015-10-01