One Step Ahead: Herpesviruses Light the Way to Understanding Interferon-Stimulated Genes (ISGs)

by A. Cristina Gonzalez-Perez, Markus Stempel, Markus Stempel, Baca Chan, Melanie M. Brinkmann, Melanie M. Brinkmann
Published 2020-02-01

Of Keeping and Tipping the Balance: Host Regulation and Viral Modulation of IRF3-Dependent <i>IFNB1</i> Expression

by Hella Schwanke, Markus Stempel, Melanie M. Brinkmann
Published 2020-07-01

UNC93B1 Is Widely Expressed in the Murine CNS and Is Required for Neuroinflammation and Neuronal Injury Induced by MicroRNA let-7b

by Markus G. Klammer, Markus G. Klammer, Omar Dzaye, Thomas Wallach, Christina Krüger, Dorothea Gaessler, Alice Buonfiglioli, Katja Derkow, Helmut Kettenmann, Melanie M. Brinkmann, Melanie M. Brinkmann, Seija Lehnardt, Seija Lehnardt
Published 2021-09-01

Murine cytomegaloviruses m139 targets DDX3 to curtail interferon production and promote viral replication.

by Olha Puhach, Eleonore Ostermann, Christoph Krisp, Giada Frascaroli, Hartmut Schlüter, Melanie M Brinkmann, Wolfram Brune
Published 2020-10-01

Viral mediated redirection of NEMO/IKKγ to autophagosomes curtails the inflammatory cascade.

by Patricia M Fliss, Tali Pechenick Jowers, Melanie M Brinkmann, Barbara Holstermann, Claudia Mack, Paul Dickinson, Heinrich Hohenberg, Peter Ghazal, Wolfram Brune
Published 2012-02-01

SARS‐CoV‐2 outbreak investigation in a German meat processing plant

by Thomas Günther, Manja Czech‐Sioli, Daniela Indenbirken, Alexis Robitaille, Peter Tenhaken, Martin Exner, Matthias Ottinger, Nicole Fischer, Adam Grundhoff, Melanie M Brinkmann
Published 2020-12-01

The Cytomegalovirus Tegument Protein UL35 Antagonizes Pattern Recognition Receptor-Mediated Type I IFN Transcription

by Markus Fabits, Vladimir Gonçalves Magalhães, Baca Chan, Virginie Girault, Endrit Elbasani, Elisa Rossetti, Eirikur Saeland, Martin Messerle, Andreas Pichlmair, Vanda Juranić Lisnić, Melanie M. Brinkmann
Published 2020-05-01

Age-dependent enterocyte invasion and microcolony formation by Salmonella.

by Kaiyi Zhang, Aline Dupont, Natalia Torow, Frederik Gohde, Sara Leschner, Stefan Lienenklaus, Siegfried Weiss, Melanie M Brinkmann, Mark Kühnel, Michael Hensel, Marcus Fulde, Mathias W Hornef
Published 2014-09-01

The interferon-stimulated gene product oligoadenylate synthetase-like protein enhances replication of Kaposi's sarcoma-associated herpesvirus (KSHV) and interacts with the KSHV ORF...

by Kendra A Bussey, Ulrike Lau, Sophie Schumann, Antonio Gallo, Lisa Osbelt, Markus Stempel, Christine Arnold, Josef Wissing, Hans Henrik Gad, Rune Hartmann, Wolfram Brune, Lothar Jänsch, Adrian Whitehouse, Melanie M Brinkmann
Published 2018-03-01

The Mouse Cytomegalovirus Gene m42 Targets Surface Expression of the Protein Tyrosine Phosphatase CD45 in Infected Macrophages.

by Nadine Thiel, Kirsten A Keyser, Niels A W Lemmermann, Jennifer D Oduro, Karen Wagner, Carina Elsner, Anne Halenius, Tihana Lenac Roviš, Melanie M Brinkmann, Stipan Jonjić, Luka Cicin-Sain, Martin Messerle
Published 2016-12-01

The murine cytomegalovirus M35 protein antagonizes type I IFN induction downstream of pattern recognition receptors by targeting NF-κB mediated transcription.

by Baca Chan, Vladimir Gonçalves Magalhães, Niels A W Lemmermann, Vanda Juranić Lisnić, Markus Stempel, Kendra A Bussey, Elisa Reimer, Jürgen Podlech, Stefan Lienenklaus, Matthias J Reddehase, Stipan Jonjić, Melanie M Brinkmann
Published 2017-05-01