Rapid and Highly Sensitive Detection of Variant Creutzfeldt-Jakob Disease Abnormal Prion Protein on Steel Surfaces by Protein Misfolding Cyclic Amplification: Application to Prion...

by Maxime Belondrade, Simon Nicot, Vincent Béringue, Joliette Coste, Sylvain Lehmann, Daisy Bougard
Published 2016-01-01

Prion replication occurs in endogenous adult neural stem cells and alters their neuronal fate: involvement of endogenous neural stem cells in prion diseases.

by Aroa Relaño-Ginès, Audrey Gabelle, Claire Hamela, Maxime Belondrade, Danielle Casanova, Chantal Mourton-Gilles, Sylvain Lehmann, Carole Crozet
Published 2013-01-01

Diagnosis of Methionine/Valine Variant Creutzfeldt-Jakob Disease by Protein Misfolding Cyclic Amplification

by Daisy Bougard, Maxime Bélondrade, Charly Mayran, Lilian Bruyère-Ostells, Sylvain Lehmann, Chantal Fournier-Wirth, Richard S. Knight, Robert G. Will, Alison J.E. Green
Published 2018-07-01

Correlation between Bioassay and Protein Misfolding Cyclic Amplification for Variant Creutzfeldt-Jakob Disease Decontamination Studies

by Maxime Bélondrade, Christelle Jas-Duval, Simon Nicot, Lilian Bruyère-Ostells, Charly Mayran, Laetitia Herzog, Fabienne Reine, Juan Maria Torres, Chantal Fournier-Wirth, Vincent Béringue, Sylvain Lehmann, Daisy Bougard
Published 2020-01-01

Sensitive protein misfolding cyclic amplification of sporadic Creutzfeldt–Jakob disease prions is strongly seed and substrate dependent

by Maxime Bélondrade, Simon Nicot, Charly Mayran, Lilian Bruyere-Ostells, Florian Almela, Michele A. Di Bari, Etienne Levavasseur, Joel C. Watts, Chantal Fournier-Wirth, Sylvain Lehmann, Stéphane Haïk, Romolo Nonno, Daisy Bougard
Published 2021-02-01

Systemic delivery of siRNA down regulates brain prion protein and ameliorates neuropathology in prion disorder.

by Sylvain Lehmann, Aroa Relano-Gines, Sarah Resina, Elsa Brillaud, Danielle Casanova, Charles Vincent, Claire Hamela, Sophie Poupeau, Mathieu Laffont, Audrey Gabelle, Constance Delaby, Maxime Belondrade, Jacques-Damien Arnaud, Maria-Teresa Alvarez, Jean-Claude Maurel, Patrick Maurel, Carole Crozet
Published 2014-01-01