Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes

by Shuang Yang, Kriti Bahl, Hui-Ting Chou, Jonathan Woodsmith, Ulrich Stelzl, Thomas Walz, Maxence V Nachury
Published 2020-06-01

Single molecule imaging reveals a major role for diffusion in the exploration of ciliary space by signaling receptors

by Fan Ye, David K Breslow, Elena F Koslover, Andrew J Spakowitz, W James Nelson, Maxence V Nachury
Published 2013-08-01

A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened.

by Seongjin Seo, Qihong Zhang, Kevin Bugge, David K Breslow, Charles C Searby, Maxence V Nachury, Val C Sheffield
Published 2011-11-01

Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action

by Jonathan B Steinman, Cristina C Santarossa, Rand M Miller, Lola S Yu, Anna S Serpinskaya, Hideki Furukawa, Sachie Morimoto, Yuta Tanaka, Mitsuyoshi Nishitani, Moriteru Asano, Ruta Zalyte, Alison E Ondrus, Alex G Johnson, Fan Ye, Maxence V Nachury, Yoshiyuki Fukase, Kazuyoshi Aso, Michael A Foley, Vladimir I Gelfand, James K Chen, Andrew P Carter, Tarun M Kapoor
Published 2017-05-01