Increased Neutrophil Secretion Induced by NLRP3 Mutation Links the Inflammasome to Azurophilic Granule Exocytosis

by Jennifer L. Johnson, Mahalakshmi Ramadass, Ariela Haimovich, Matthew D. McGeough, Jinzhong Zhang, Hal M. Hoffman, Sergio D. Catz
Published 2017-12-01

Constitutively activated NLRP3 inflammasome causes inflammation and abnormal skeletal development in mice.

by Sheri L Bonar, Susannah D Brydges, James L Mueller, Matthew D McGeough, Carla Pena, Debbie Chen, Susan K Grimston, Cynthia L Hickman-Brecks, Soumya Ravindran, Audrey McAlinden, Deborah V Novack, Daniel L Kastner, Roberto Civitelli, Hal M Hoffman, Gabriel Mbalaviele
Published 2012-01-01

Mutations in topoisomerase IIβ result in a B cell immunodeficiency

by Lori Broderick, Shawn Yost, Dong Li, Matthew D. McGeough, Laela M. Booshehri, Marisela Guaderrama, Susannah D. Brydges, Karolina Kucharova, Niraj C. Patel, Margaret Harr, Hakon Hakonarson, Elaine Zackai, Ian G. Cowell, Caroline A. Austin, Boris Hügle, Corinna Gebauer, Jianguo Zhang, Xun Xu, Jian Wang, Ben A. Croker, Kelly A. Frazer, Christopher D. Putnam, Hal M. Hoffman
Published 2019-08-01