Cross-Linking Cellular Prion Protein Induces Neuronal Type 2-Like Hypersensitivity

by Utpal Kumar Adhikari, Elif Sakiz, Xian Zhou, Umma Habiba, Sachin Kumar, Meena Mikhael, Matteo Senesi, Matteo Senesi, Chun Guang Li, Gilles J. Guillemin, Lezanne Ooi, Lezanne Ooi, Monique Antoinette David, Steven Collins, Steven Collins, Tim Karl, Tim Karl, Tim Karl, Mourad Tayebi
Published 2021-07-01

Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc.

by Simote Totauhelotu Foliaki, Victoria Lewis, Abu Mohammed Taufiqual Islam, Laura Jane Ellett, Matteo Senesi, David Isaac Finkelstein, Blaine Roberts, Victoria A Lawson, Paul Anthony Adlard, Steven John Collins
Published 2019-04-01

Prion acute synaptotoxicity is largely driven by protease-resistant PrPSc species.

by Simote Totauhelotu Foliaki, Victoria Lewis, David Isaac Finkelstein, Victoria Lawson, Harold Arthur Coleman, Matteo Senesi, Abu Mohammed Taufiqual Islam, Feng Chen, Shannon Sarros, Blaine Roberts, Paul Anthony Adlard, Steven John Collins
Published 2018-08-01