Editorial: Macrophage Metabolism and Immune Responses

by Héctor Rodríguez, Rafael Prados-Rosales, José Luis Lavín, Massimiliano Mazzone, Massimiliano Mazzone, Juan Anguita, Juan Anguita
Published 2020-05-01

Understanding Metal Dynamics Between Cancer Cells and Macrophages: Competition or Synergism?

by Marina Serra, Marina Serra, Amedeo Columbano, Ummi Ammarah, Ummi Ammarah, Massimiliano Mazzone, Massimiliano Mazzone, Alessio Menga, Alessio Menga
Published 2020-04-01

Isolation and separation of murine tumor-associated macrophages (TAMs) subpopulations from orthotopic 4T1 breast tumors

by Pawel Bieniasz-Krzywiec, Rosa Martín-Pérez, Carla Riera-Domingo, Massimiliano Mazzone
Published 2021-06-01

MicroRNA-Mediated Metabolic Shaping of the Tumor Microenvironment

by Federico Virga, Lorena Quirico, Stefania Cucinelli, Massimiliano Mazzone, Daniela Taverna, Francesca Orso
Published 2021-01-01

PHD2 Targeting Overcomes Breast Cancer Cell Death upon Glucose Starvation in a PP2A/B55α-Mediated Manner

by Giusy Di Conza, Sarah Trusso Cafarello, Xingnan Zheng, Qing Zhang, Massimiliano Mazzone
Published 2017-03-01

Loss of Caveolin-1 in Metastasis-Associated Macrophages Drives Lung Metastatic Growth through Increased Angiogenesis

by Ward Celus, Giusy Di Conza, Ana Isabel Oliveira, Manuel Ehling, Bruno M. Costa, Mathias Wenes, Massimiliano Mazzone
Published 2017-12-01

The anti-proliferative effect of L-carnosine correlates with a decreased expression of hypoxia inducible factor 1 alpha in human colon cancer cells.

by Barbara Iovine, Giorgia Oliviero, Mariangela Garofalo, Maria Orefice, Francesca Nocella, Nicola Borbone, Vincenzo Piccialli, Roberto Centore, Massimiliano Mazzone, Gennaro Piccialli, Maria Assunta Bevilacqua
Published 2014-01-01

miR-511-3p Modulates Genetic Programs of Tumor-Associated Macrophages

by Mario Leonardo Squadrito, Ferdinando Pucci, Laura Magri, Davide Moi, Gregor D. Gilfillan, Anna Ranghetti, Andrea Casazza, Massimiliano Mazzone, Robert Lyle, Luigi Naldini, Michele De Palma
Published 2012-02-01

Histidine-rich glycoprotein uptake and turnover is mediated by mononuclear phagocytes.

by Sònia Tugues, Francis Roche, Oriol Noguer, Anna Orlova, Sujata Bhoi, Narendra Padhan, Peter Akerud, Satoshi Honjo, Ram Kumar Selvaraju, Massimiliano Mazzone, Vladimir Tolmachev, Lena Claesson-Welsh
Published 2014-01-01

Correction: Hypoxia-induced miR-210 modulates the inflammatory response and fibrosis upon acute ischemia

by Germana Zaccagnini, Simona Greco, Marialucia Longo, Biagina Maimone, Christine Voellenkle, Paola Fuschi, Matteo Carrara, Pasquale Creo, Davide Maselli, Mario Tirone, Massimiliano Mazzone, Carlo Gaetano, Gaia Spinetti, Fabio Martelli
Published 2021-05-01

Protein Phosphatase 2A Mediates YAP Activation in Endothelial Cells Upon VEGF Stimulation and Matrix Stiffness

by Xiao Jiang, Jiandong Hu, Ziru Wu, Sarah Trusso Cafarello, Mario Di Matteo, Ying Shen, Xue Dong, Xue Dong, Heike Adler, Massimiliano Mazzone, Carmen Ruiz de Almodovar, Xiaohong Wang, Xiaohong Wang
Published 2021-05-01

The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia

by Giusy Di Conza, Sarah Trusso Cafarello, Stefan Loroch, Daniela Mennerich, Sofie Deschoemaeker, Mario Di Matteo, Manuel Ehling, Kris Gevaert, Hans Prenen, Rene Peiman Zahedi, Albert Sickmann, Thomas Kietzmann, Fabiola Moretti, Massimiliano Mazzone
Published 2017-02-01

Glufosinate constrains synchronous and metachronous metastasis by promoting anti‐tumor macrophages

by Alessio Menga, Marina Serra, Simona Todisco, Carla Riera‐Domingo, Ummi Ammarah, Manuel Ehling, Erika M Palmieri, Maria Antonietta Di Noia, Rosanna Gissi, Maria Favia, Ciro L Pierri, Paolo E Porporato, Alessandra Castegna, Massimiliano Mazzone
Published 2020-10-01

Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis

by Erika M. Palmieri, Alessio Menga, Rosa Martín-Pérez, Annamaria Quinto, Carla Riera-Domingo, Giacoma De Tullio, Douglas C. Hooper, Wouter H. Lamers, Bart Ghesquière, Daniel W. McVicar, Attilio Guarini, Massimiliano Mazzone, Alessandra Castegna
Published 2017-08-01

Targeting Neuropilin-1 with Nanobodies Reduces Colorectal Carcinoma Development

by Yannick De De Vlaeminck, Stefano Bonelli, Robin Maximilian Awad, Maarten Dewilde, Sabrina Rizzolio, Quentin Lecocq, Evangelia Bolli, Ana Rita Santos, Damya Laoui, Steve Schoonooghe, Luca Tamagnone, Cleo Goyvaerts, Massimiliano Mazzone, Karine Breckpot, Jo A. Van Ginderachter
Published 2020-11-01

Differential Effects of Trp53 Alterations in Murine Colorectal Cancer

by Alexander M. Betzler, Lahiri K. Nanduri, Barbara Hissa, Linda Blickensdörfer, Michael H. Muders, Janine Roy, Moritz Jesinghaus, Katja Steiger, Wilko Weichert, Matthias Kloor, Barbara Klink, Michael Schroeder, Massimiliano Mazzone, Jürgen Weitz, Christoph Reissfelder, Nuh N. Rahbari, Sebastian Schölch
Published 2021-02-01

The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity

by Damya Laoui, Jiri Keirsse, Yannick Morias, Eva Van Overmeire, Xenia Geeraerts, Yvon Elkrim, Mate Kiss, Evangelia Bolli, Qods Lahmar, Dorine Sichien, Jens Serneels, Charlotte L. Scott, Louis Boon, Patrick De Baetselier, Massimiliano Mazzone, Martin Guilliams, Jo A. Van Ginderachter
Published 2016-12-01

Brain endothelial cells control fertility through ovarian-steroid-dependent release of semaphorin 3A.

by Paolo Giacobini, Jyoti Parkash, Céline Campagne, Andrea Messina, Filippo Casoni, Charlotte Vanacker, Fanny Langlet, Barbara Hobo, Gabriella Cagnoni, Sarah Gallet, Naresh Kumar Hanchate, Danièle Mazur, Masahiko Taniguchi, Massimiliano Mazzone, Joost Verhaagen, Philippe Ciofi, Sébastien G Bouret, Luca Tamagnone, Vincent Prevot
Published 2014-03-01

Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer

by Marina Bacci, Nicla Lorito, Luigi Ippolito, Matteo Ramazzotti, Simone Luti, Simone Romagnoli, Matteo Parri, Francesca Bianchini, Federica Cappellesso, Federico Virga, Qiong Gao, Bruno M. Simões, Elisabetta Marangoni, Lesley-Ann Martin, Giuseppina Comito, Manuela Ferracin, Elisa Giannoni, Massimiliano Mazzone, Paola Chiarugi, Andrea Morandi
Published 2019-07-01

MIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African Trypanosomosis.

by Benoît Stijlemans, Lea Brys, Hannelie Korf, Pawel Bieniasz-Krzywiec, Amanda Sparkes, Liese Vansintjan, Lin Leng, Nele Vanbekbergen, Massimiliano Mazzone, Guy Caljon, Jan Van Den Abbeele, Steven Odongo, Carl De Trez, Stefan Magez, Jo A Van Ginderachter, Alain Beschin, Richard Bucala, Patrick De Baetselier
Published 2016-09-01