Mitotic UV irradiation induces a DNA replication-licensing defect that potentiates G1 arrest response.

by Masayuki Morino, Kohei Nukina, Hiroki Sakaguchi, Takeshi Maeda, Michiyo Takahara, Yasushi Shiomi, Hideo Nishitani
Published 2015-01-01

Checkpoint kinase ATR phosphorylates Cdt2, a substrate receptor of CRL4 ubiquitin ligase, and promotes the degradation of Cdt1 following UV irradiation.

by Hiroki Sakaguchi, Toshihiro Takami, Yoshinori Yasutani, Takeshi Maeda, Masayuki Morino, Takashi Ishii, Yasushi Shiomi, Hideo Nishitani
Published 2012-01-01