Hypoxia in Diabetic Kidneys

by Yumi Takiyama, Masakazu Haneda
Published 2014-01-01

Role of IGFBP7 in Diabetic Nephropathy: TGF-β1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells.

by Jun Watanabe, Yumi Takiyama, Jun Honjyo, Yuichi Makino, Yukihiro Fujita, Masatoshi Tateno, Masakazu Haneda
Published 2016-01-01

Receptor-Mediated Bioassay Reflects Dynamic Change of Glucose-Dependent Insulinotropic Polypeptide by Dipeptidyl Peptidase 4 Inhibitor Treatment in Subjects With Type 2 Diabetes

by Tsuyoshi Yanagimachi, Yukihiro Fujita, Yukihiro Fujita, Yasutaka Takeda, Jun Honjo, Jun Honjo, Hiroki Yokoyama, Masakazu Haneda
Published 2020-04-01

Establishment of novel specific assay for short‐form glucose‐dependent insulinotropic polypeptide and evaluation of its secretion in nondiabetic subjects

by Yasutaka Takeda, Yukihiro Fujita, Tsuyoshi Yanagimachi, Nobuhiro Maruyama, Ryoichi Bessho, Hidemitsu Sakagami, Jun Honjo, Hiroki Yokoyama, Masakazu Haneda
Published 2020-06-01

Octreotide-Treated Diabetes Accompanied by Endogenous Hyperinsulinemic Hypoglycemia and Protein-Losing Gastroenteropathy

by Nobuhiko Takahashi, Miho Nagamine, Mitsuko Fukuda, Wataru Motomura, Atsuko Abiko, Masakazu Haneda, Mikihiro Fujiya, Masahiro Ieko, Yutaka Kohgo
Published 2011-01-01

Oral Administration of N-Acetyl-seryl-aspartyl-lysyl-proline Ameliorates Kidney Disease in Both Type 1 and Type 2 Diabetic Mice via a Therapeutic Regimen

by Kyoko Nitta, Sen Shi, Takako Nagai, Megumi Kanasaki, Munehiro Kitada, Swayam Prakash Srivastava, Masakazu Haneda, Keizo Kanasaki, Daisuke Koya
Published 2016-01-01

Secular changes in clinical manifestations of kidney disease among Japanese adults with type 2 diabetes from 1996 to 2014

by Shinji Kume, Shin‐ichi Araki, Satoshi Ugi, Katsutaro Morino, Daisuke Koya, Yoshihiko Nishio, Masakazu Haneda, Atsunori Kashiwagi, Hiroshi Maegawa
Published 2019-07-01

Sodium-Glucose Cotransporter 2 Inhibitor and a Low Carbohydrate Diet Affect Gluconeogenesis and Glycogen Content Differently in the Kidney and the Liver of Non-Diabetic Mice.

by Kuralay Atageldiyeva, Yukihiro Fujita, Tsuyoshi Yanagimachi, Katsutoshi Mizumoto, Yasutaka Takeda, Jun Honjo, Yumi Takiyama, Atsuko Abiko, Yuichi Makino, Masakazu Haneda
Published 2016-01-01

A Low-Carbohydrate Diet Improves Glucose Metabolism in Lean Insulinopenic Akita Mice Along With Sodium-Glucose Cotransporter 2 Inhibitor

by Yukihiro Fujita, Yukihiro Fujita, Kuralay K. Atageldiyeva, Kuralay K. Atageldiyeva, Yasutaka Takeda, Tsuyoshi Yanagimachi, Tsuyoshi Yanagimachi, Yuichi Makino, Yuichi Makino, Masakazu Haneda
Published 2020-12-01

Increment of plasma glucose by exogenous glucagon is associated with present and future renal function in type 2 diabetes:a retrospective study from glucagon stimulation test

by Yasutaka Takeda, Yukihiro Fujita, Ryoichi Bessho, Mao Sato, Tomoe Abe, Tsuyoshi Yanagimachi, Hidemitsu Sakagami, Atsuko Abiko, Yumi Takiyama, Tsuguhito Ota, Masakazu Haneda
Published 2019-10-01

Expression of transcription factors in MEN1-associated pancreatic neuroendocrine tumors

by Yasutaka Takeda, Yukihiro Fujita, Kentaro Sakai, Tomoe Abe, Tomonobu Nakamura, Tsuyoshi Yanagimachi, Hidemitsu Sakagami, Jun Honjo, Atsuko Abiko, Yuichi Makino, Masakazu Haneda
Published 2017-09-01

Dipeptidyl peptidase-4 inhibitor treatment induces a greater increase in plasma levels of bioactive GIP than GLP-1 in non-diabetic subjects

by Tsuyoshi Yanagimachi, Yukihiro Fujita, Yasutaka Takeda, Jun Honjo, Hidemitsu Sakagami, Hiroya Kitsunai, Yumi Takiyama, Atsuko Abiko, Yuichi Makino, Timothy J. Kieffer, Masakazu Haneda
Published 2017-02-01

Predictive properties of plasma amino acid profile for cardiovascular disease in patients with type 2 diabetes.

by Shinji Kume, Shin-ichi Araki, Nobukazu Ono, Atsuko Shinhara, Takahiko Muramatsu, Hisazumi Araki, Keiji Isshiki, Kazuki Nakamura, Hiroshi Miyano, Daisuke Koya, Masakazu Haneda, Satoshi Ugi, Hiromichi Kawai, Atsunori Kashiwagi, Takashi Uzu, Hiroshi Maegawa
Published 2014-01-01

GW501516, a PPARδ agonist, ameliorates tubulointerstitial inflammation in proteinuric kidney disease via inhibition of TAK1-NFκB pathway in mice.

by Xu Yang, Shinji Kume, Yuki Tanaka, Keiji Isshiki, Shin-ichi Araki, Masami Chin-Kanasaki, Toshiro Sugimoto, Daisuke Koya, Masakazu Haneda, Takeshi Sugaya, Detian Li, Ping Han, Yoshihiko Nishio, Atsunori Kashiwagi, Hiroshi Maegawa, Takashi Uzu
Published 2011-01-01

Impacts of Diabetes and an SGLT2 Inhibitor on the Glomerular Number and Volume in db/db Mice, as Estimated by Synchrotron Radiation Micro-CT at SPring-8Research in context

by Yumi Takiyama, Toshihiro Sera, Masanori Nakamura, Kanaki Ishizeki, Yasuaki Saijo, Tsuyoshi Yanagimachi, Manami Maeda, Ryoichi Bessho, Takao Takiyama, Hiroya Kitsunai, Hidemitsu Sakagami, Daisuke Fujishiro, Yukihiro Fujita, Yuichi Makino, Atsuko Abiko, Masato Hoshino, Kentaro Uesugi, Naoto Yagi, Tsuguhito Ota, Masakazu Haneda
Published 2018-10-01

Hypothalamic AMP-Activated Protein Kinase Regulates Biphasic Insulin Secretion from Pancreatic β Cells during Fasting and in Type 2 Diabetes

by Shinji Kume, Motoyuki Kondo, Shiro Maeda, Yoshihiko Nishio, Tsuyoshi Yanagimachi, Yukihiro Fujita, Masakazu Haneda, Keiko Kondo, Akihiro Sekine, Shin-ich Araki, Hisazumi Araki, Masami Chin-Kanasaki, Satoshi Ugi, Daisuke Koya, Sawako Kitahara, Kiyosumi Maeda, Atsunori Kashiwagi, Takashi Uzu, Hiroshi Maegawa
Published 2016-11-01

Randomized trial of an intensified, multifactorial intervention in patients with advanced‐stage diabetic kidney disease: Diabetic Nephropathy Remission and Regression Team Trial in...

by Kenichi Shikata, Masakazu Haneda, Toshiharu Ninomiya, Daisuke Koya, Yoshiki Suzuki, Daisuke Suzuki, Hitoshi Ishida, Hiroaki Akai, Yasuhiko Tomino, Takashi Uzu, Motonobu Nishimura, Shiro Maeda, Daisuke Ogawa, Satoshi Miyamoto, Hirofumi Makino, the Diabetic Nephropathy Remission and Regression Team Trial in Japan (DNETT‐Japan) collaborative group
Published 2021-02-01

Combined changes in albuminuria and kidney function and subsequent risk for kidney failure in type 2 diabetes

by Toshiharu Ninomiya, Hiroki Yokoyama, Shin-ichi Araki, Hirofumi Makino, Kunitoshi Iseki, Kengo Furuichi, Megumi Oshima, Tadashi Toyama, Takashi Wada, Miho Shimizu, Hiroyuki Nakamura, Norihiko Sakai, Yasunori Iwata, Shinji Kitajima, Akinori Hara, Yoshiki Suzuki, Hiroaki Satoh, Tetsuya Babazono, Tatsumi Moriya, Masayuki Iwano, Masakazu Haneda, Shigeko Hara, Eiji Kusano
Published 2021-08-01

Estimated glomerular filtration rate decline and risk of end-stage renal disease in type 2 diabetes.

by Megumi Oshima, Tadashi Toyama, Masakazu Haneda, Kengo Furuichi, Tetsuya Babazono, Hiroki Yokoyama, Kunitoshi Iseki, Shinichi Araki, Toshiharu Ninomiya, Shigeko Hara, Yoshiki Suzuki, Masayuki Iwano, Eiji Kusano, Tatsumi Moriya, Hiroaki Satoh, Hiroyuki Nakamura, Miho Shimizu, Akinori Hara, Hirofumi Makino, Takashi Wada, Research Group of Diabetic Nephropathy, Ministry of Health, Labour, and Welfare of Japan
Published 2018-01-01

Comparative Effects of Direct Renin Inhibitor and Angiotensin Receptor Blocker on Albuminuria in Hypertensive Patients with Type 2 Diabetes. A Randomized Controlled Trial.

by Takashi Uzu, Shin-Ichi Araki, Atsunori Kashiwagi, Masakazu Haneda, Daisuke Koya, Hiroki Yokoyama, Yasuo Kida, Motoyoshi Ikebuchi, Takaaki Nakamura, Masataka Nishimura, Noriko Takahara, Toshiyuki Obata, Nobuyuki Omichi, Katsuhiko Sakamoto, Ryosuke Shingu, Hideki Taki, Yoshio Nagai, Hiroaki Tokuda, Munehiro Kitada, Miwa Misawa, Akira Nishiyama, Hiroyuki Kobori, Hiroshi Maegawa, Shiga Committee for Preventing Diabetic Nephropathy
Published 2016-01-01