OPRD1 SNPs associated with opioid addiction are cis-eQTLs for the phosphatase and actin regulator 4 gene, PHACTR4, a mediator of cytoskeletal dynamics

by Orna Levran, Matthew Randesi, Miriam Adelson, Mary Jeanne Kreek
Published 2021-05-01

A 3' UTR SNP rs885863, a cis-eQTL for the circadian gene VIPR2 and lincRNA 689, is associated with opioid addiction.

by Orna Levran, Matthew Randesi, John Rotrosen, Jurg Ott, Miriam Adelson, Mary Jeanne Kreek
Published 2019-01-01

A non-coding CRHR2 SNP rs255105, a cis-eQTL for a downstream lincRNA AC005154.6, is associated with heroin addiction.

by Orna Levran, Joel Correa da Rosa, Matthew Randesi, John Rotrosen, Miriam Adelson, Mary Jeanne Kreek
Published 2018-01-01

Non-medical Cannabis Self-Exposure as a Dimensional Predictor of Opioid Dependence Diagnosis: A Propensity Score Matched Analysis

by Eduardo R. Butelman, Angelo G. I. Maremmani, Silvia Bacciardi, Carina Y. Chen, Joel Correa da Rosa, Mary Jeanne Kreek
Published 2018-06-01

Sex differences after chronic stress in the expression of opioid-, stress- and neuroplasticity-related genes in the rat hippocampus

by Matthew Randesi, Yan Zhou, Sanoara Mazid, Shannon C. Odell, Jason D. Gray, J. Correa da Rosa, Bruce S. McEwen, Teresa A. Milner, Mary Jeanne Kreek
Published 2018-02-01

Fructose:Glucose Ratios—A Study of Sugar Self-Administration and Associated Neural and Physiological Responses in the Rat

by AnneMarie Levy, Paul Marshall, Yan Zhou, Mary Jeanne Kreek, Katrina Kent, Stephen Daniels, Ari Shore, Tiana Downs, Maria Fernanda Fernandes, David M. Mutch, Francesco Leri
Published 2015-05-01

Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent

by Sidnee L. Hedrick, Dan Luo, Sophia Kaska, Kumar Kulldeep Niloy, Karen Jackson, Rupam Sarma, Jamie Horn, Caroline Baynard, Markos Leggas, Eduardo R. Butelman, Mary Jeanne Kreek, Thomas E. Prisinzano
Published 2021-09-01

Sex and chronic stress alter delta opioid receptor distribution within rat hippocampal CA1 pyramidal cells following behavioral challenges

by Batsheva R. Rubin, Megan A. Johnson, Jared M. Berman, Ellen Goldstein, Vera Pertsovskaya, Yan Zhou, Natalina H. Contoreggi, Andreina G. Dyer, Jason D. Gray, Elizabeth M. Waters, Bruce S. McEwen, Mary Jeanne Kreek, Teresa A. Milner
Published 2020-11-01

Association of Variants of Arginine Vasopressin and Arginine Vasopressin Receptor 1A With Severe Acetaminophen Liver InjurySummary

by Matthew Randesi, Orna Levran, Joel Correa da Rosa, Julia Hankins, Jody Rule, Mary Jeanne Kreek, William M. Lee, Adrian Reuben, Robert J. Fontana, Timothy Davern, Brendan McGuire, R. Todd Stravitz, Valerie Durkalski, Iris Liou, Oren Fix, Michael Schilsky, Daniel Ganger, MD, Raymond T. Chung, David Koch, K. Rajender Reddy, Lorenzo Rossaro
Published 2017-05-01