A Bayesian machine learning approach for drug target identification using diverse data types

by Neel S. Madhukar, Prashant K. Khade, Linda Huang, Kaitlyn Gayvert, Giuseppe Galletti, Martin Stogniew, Joshua E. Allen, Paraskevi Giannakakou, Olivier Elemento
Published 2019-11-01

ONC201 and imipridones: Anti-cancer compounds with clinical efficacy

by Varun Vijay Prabhu, Sara Morrow, Abed Rahman Kawakibi, Lanlan Zhou, Marie Ralff, Jocelyn Ray, Aakash Jhaveri, Isacco Ferrarini, Young Lee, Cassandra Parker, Yiqun Zhang, Robyn Borsuk, Wen-I Chang, Joshua N. Honeyman, Fabio Tavora, Benedito Carneiro, Alexander Raufi, Kelsey Huntington, Lindsey Carlsen, Anna Louie, Howard Safran, Attila A. Seyhan, Rohinton S. Tarapore, Lee Schalop, Martin Stogniew, Joshua E. Allen, Wolfgang Oster, Wafik S. El-Deiry
Published 2020-12-01

Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration

by Mark N. Stein, Jyoti Malhotra, Rohinton S. Tarapore, Usha Malhotra, Ann W. Silk, Nancy Chan, Lorna Rodriguez, Joseph Aisner, Robert D. Aiken, Tina Mayer, Bruce G. Haffty, Jenna H. Newman, Salvatore M. Aspromonte, Praveen K. Bommareddy, Ricardo Estupinian, Charles B. Chesson, Evita T. Sadimin, Shengguo Li, Daniel J. Medina, Tracie Saunders, Melissa Frankel, Aparna Kareddula, Sherrie Damare, Elayne Wesolowsky, Christian Gabel, Wafik S. El-Deiry, Varun V. Prabhu, Joshua E. Allen, Martin Stogniew, Wolfgang Oster, Joseph R. Bertino, Steven K. Libutti, Janice M. Mehnert, Andrew Zloza
Published 2019-05-01