Structural insights into the molecular mechanism of the m6A writer complex

by Paweł Śledź, Martin Jinek
Published 2016-09-01

Structural insights into the assembly and polyA signal recognition mechanism of the human CPSF complex

by Marcello Clerici, Marco Faini, Ruedi Aebersold, Martin Jinek
Published 2017-12-01

RNA-programmed genome editing in human cells

by Martin Jinek, Alexandra East, Aaron Cheng, Steven Lin, Enbo Ma, Jennifer Doudna
Published 2013-01-01

Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations

by Giulia Palermo, Yinglong Miao, Ross C. Walker, Martin Jinek, J. Andrew McCammon
Published 2016-09-01

CRISPR-Directed Therapeutic Correction at the NCF1 Locus Is Challenged by Frequent Incidence of Chromosomal Deletions

by Dominik Wrona, Oleksandr Pastukhov, Robert S. Pritchard, Federica Raimondi, Joëlle Tchinda, Martin Jinek, Ulrich Siler, Janine Reichenbach
Published 2020-06-01

Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6

by Carmela Garcia-Doval, Frank Schwede, Christian Berk, Jakob T. Rostøl, Ole Niewoehner, Oliver Tejero, Jonathan Hall, Luciano A. Marraffini, Martin Jinek
Published 2020-03-01

Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair

by Natasa Savic, Femke CAS Ringnalda, Helen Lindsay, Christian Berk, Katja Bargsten, Yizhou Li, Dario Neri, Mark D Robinson, Constance Ciaudo, Jonathan Hall, Martin Jinek, Gerald Schwank
Published 2018-05-01

Hakai is required for stabilization of core components of the m6A mRNA methylation machinery

by Praveen Bawankar, Tina Lence, Chiara Paolantoni, Irmgard U. Haussmann, Migle Kazlauskiene, Dominik Jacob, Jan B. Heidelberger, Florian M. Richter, Mohanakarthik P. Nallasivan, Violeta Morin, Nastasja Kreim, Petra Beli, Mark Helm, Martin Jinek, Matthias Soller, Jean-Yves Roignant
Published 2021-06-01

An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish

by Jun Zou, Diana Tran, Mai Baalbaki, Ling Fung Tang, Annie Poon, Angelo Pelonero, Erron W Titus, Christiana Yuan, Chenxu Shi, Shruthi Patchava, Elizabeth Halper, Jasmine Garg, Irina Movsesyan, Chaoying Yin, Roland Wu, Lisa D Wilsbacher, Jiandong Liu, Ronald L Hager, Shaun R Coughlin, Martin Jinek, Clive R Pullinger, John P Kane, Daniel O Hart, Pui-Yan Kwok, Rahul C Deo
Published 2015-10-01