γ-Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status

by Vijay K. Singh, Martin Hauer-Jensen
Published 2016-05-01

The Vitamin E Analog Gamma-Tocotrienol (GT3) and Statins Synergistically Up-Regulate Endothelial Thrombomodulin (TM)

by Rupak Pathak, Sanchita P. Ghosh, Daohong Zhou, Martin Hauer-Jensen
Published 2016-11-01

Laser capture microdissected mucosa versus whole tissue specimens for assessment of radiation-induced dynamic molecular and pathway changes in the small intestine.

by Junying Zheng, Sarita Garg, Junru Wang, David S Loose, Martin Hauer-Jensen
Published 2013-01-01

Pharmacological induction of transforming growth factor-beta1 in rat models enhances radiation injury in the intestine and the heart.

by Marjan Boerma, Junru Wang, Vijayalakshmi Sridharan, Jean-Marc Herbert, Martin Hauer-Jensen
Published 2013-01-01

Thrombomodulin contributes to gamma tocotrienol-mediated lethality protection and hematopoietic cell recovery in irradiated mice.

by Rupak Pathak, Lijian Shao, Sanchita P Ghosh, Daohong Zhou, Marjan Boerma, Hartmut Weiler, Martin Hauer-Jensen
Published 2015-01-01

Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model.

by Chhanda Bose, Sanjay Awasthi, Rajendra Sharma, Helen Beneš, Martin Hauer-Jensen, Marjan Boerma, Sharda P Singh
Published 2018-01-01

Cebpd Is Essential for Gamma-Tocotrienol Mediated Protection against Radiation-Induced Hematopoietic and Intestinal Injury

by Sudip Banerjee, Sumit K. Shah, Stepan B. Melnyk, Rupak Pathak, Martin Hauer-Jensen, Snehalata A. Pawar
Published 2018-04-01

Modulation of Radiation Response by the Tetrahydrobiopterin Pathway

by Rupak Pathak, Amrita K. Cheema, Simina M. Boca, Kimberly J. Krager, Martin Hauer-Jensen, Nukhet Aykin-Burns
Published 2015-01-01

IKKβ regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells.

by Lixian Wu, Lijian Shao, Ningfei An, Junru Wang, Senthil Pazhanisamy, Wei Feng, Martin Hauer-Jensen, Shigeki Miyamoto, Daohong Zhou
Published 2011-04-01

Dietary Methionine Deficiency Enhances Genetic Instability in Murine Immune Cells

by Regina L. Binz, Ratan Sadhukhan, Isabelle R. Miousse, Sarita Garg, Igor Koturbash, Daohong Zhou, Martin Hauer-Jensen, Rupak Pathak
Published 2021-02-01

Space-type radiation induces multimodal responses in the mouse gut microbiome and metabolome

by David Casero, Kirandeep Gill, Vijayalakshmi Sridharan, Igor Koturbash, Gregory Nelson, Martin Hauer-Jensen, Marjan Boerma, Jonathan Braun, Amrita K. Cheema
Published 2017-08-01

Time- and radiation-dose dependent changes in the plasma proteome after total body irradiation of non-human primates: Implications for biomarker selection.

by Stephanie D Byrum, Marie S Burdine, Lisa Orr, Samuel G Mackintosh, Simon Authier, Mylene Pouliot, Martin Hauer-Jensen, Alan J Tackett
Published 2017-01-01

Effects of late administration of pentoxifylline and tocotrienols in an image-guided rat model of localized heart irradiation.

by Vijayalakshmi Sridharan, Preeti Tripathi, Sunil Sharma, Peter M Corry, Eduardo G Moros, Awantika Singh, Cesar M Compadre, Martin Hauer-Jensen, Marjan Boerma
Published 2013-01-01

Plasma Metabolomics in a Nonhuman Primate Model of Abdominal Radiation Exposure

by Se-Ran Jun, Marjan Boerma, Zulema Udaondo, Sasha Richardson, Karla D. Thrall, Isabelle R. Miousse, John Seng, Rupak Pathak, Martin Hauer-Jensen
Published 2021-08-01

Tocotrienol-Rich Fraction from Rice Bran Demonstrates Potent Radiation Protection Activity

by Kimberly J. Krager, E. Nathalie Pineda, Sujay V. Kharade, Mary Kordsmeier, Luke Howard, Philip J. Breen, Cesar M. Compadre, Martin Hauer-Jensen, Nukhet Aykin-Burns
Published 2015-01-01

Effects of low-dose rate γ-irradiation combined with simulated microgravity on markers of oxidative stress, DNA methylation potential, and remodeling in the mouse heart.

by John W Seawright, Yusra Samman, Vijayalakshmi Sridharan, Xiao Wen Mao, Maohua Cao, Preeti Singh, Stepan Melnyk, Igor Koturbash, Gregory A Nelson, Martin Hauer-Jensen, Marjan Boerma
Published 2017-01-01

C/EBPδ deficiency sensitizes mice to ionizing radiation-induced hematopoietic and intestinal injury.

by Snehalata A Pawar, Lijian Shao, Jianhui Chang, Wenze Wang, Rupak Pathak, Xiaoyan Zhu, Junru Wang, Howard Hendrickson, Marjan Boerma, Esta Sterneck, Daohong Zhou, Martin Hauer-Jensen
Published 2014-01-01

Low doses of oxygen ion irradiation cause long-term damage to bone marrow hematopoietic progenitor and stem cells in mice.

by Yingying Wang, Jianhui Chang, Xin Li, Rupak Pathak, Vijayalakshmi Sridharan, Tamako Jones, Xiao Wen Mao, Gregory Nelson, Marjan Boerma, Martin Hauer-Jensen, Daohong Zhou, Lijian Shao
Published 2017-01-01

Low Doses of Oxygen Ion Irradiation Cause Acute Damage to Hematopoietic Cells in Mice.

by Jianhui Chang, Yi Luo, Yingying Wang, Rupak Pathak, Vijayalakshmi Sridharan, Tamako Jones, Xiao Wen Mao, Gregory Nelson, Marjan Boerma, Martin Hauer-Jensen, Daohong Zhou, Lijian Shao
Published 2016-01-01

Inter-Strain Differences in LINE-1 DNA Methylation in the Mouse Hematopoietic System in Response to Exposure to Ionizing Radiation

by Isabelle R. Miousse, Jianhui Chang, Lijian Shao, Rupak Pathak, Étienne Nzabarushimana, Kristy R. Kutanzi, Reid D. Landes, Alan J. Tackett, Martin Hauer-Jensen, Daohong Zhou, Igor Koturbash
Published 2017-07-01