Protein Complex Organization Imposes Constraints on Proteome Dysregulation in Cancer

by Gökçe Senger, Martin H. Schaefer
Published 2021-08-01

A network of epigenetic modifiers and DNA repair genes controls tissue-specific copy number alteration preference

by Dina Cramer, Luis Serrano, Martin H Schaefer
Published 2016-11-01

Translational efficiency across healthy and tumor tissues is proliferation‐related

by Xavier Hernandez‐Alias, Hannah Benisty, Martin H Schaefer, Luis Serrano
Published 2020-03-01

Translational efficiency across healthy and tumor tissues is proliferation‐related

by Xavier Hernandez‐Alias, Hannah Benisty, Martin H Schaefer, Luis Serrano
Published 2021-03-01

Protein conservation and variation suggest mechanisms of cell type-specific modulation of signaling pathways.

by Martin H Schaefer, Jae-Seong Yang, Luis Serrano, Christina Kiel
Published 2014-06-01

Correcting for the study bias associated with protein-protein interaction measurements reveals differences between protein degree distributions from different cancer types

by Martin H Schaefer, Martin H Schaefer, Luis eSerrano, Luis eSerrano, Luis eSerrano, Miguel A Andrade-Navarro, Miguel A Andrade-Navarro
Published 2015-08-01

Negative selection in tumor genome evolution acts on essential cellular functions and the immunopeptidome

by Luis Zapata, Oriol Pich, Luis Serrano, Fyodor A. Kondrashov, Stephan Ossowski, Martin H. Schaefer
Published 2018-05-01

HIPPIE: Integrating protein interaction networks with experiment based quality scores.

by Martin H Schaefer, Jean-Fred Fontaine, Arunachalam Vinayagam, Pablo Porras, Erich E Wanker, Miguel A Andrade-Navarro
Published 2012-01-01

Functional and genomic analyses of alpha-solenoid proteins.

by David Fournier, Gareth A Palidwor, Sergey Shcherbinin, Angelika Szengel, Martin H Schaefer, Carol Perez-Iratxeta, Miguel A Andrade-Navarro
Published 2013-01-01

Spatiotemporal Proteomic Profiling of Huntington’s Disease Inclusions Reveals Widespread Loss of Protein Function

by Fabian Hosp, Sara Gutiérrez-Ángel, Martin H. Schaefer, Jürgen Cox, Felix Meissner, Mark S. Hipp, F.-Ulrich Hartl, Rüdiger Klein, Irina Dudanova, Matthias Mann
Published 2017-11-01

Silencing of SRRM4 suppresses microexon inclusion and promotes tumor growth across cancers.

by Sarah A Head, Xavier Hernandez-Alias, Jae-Seong Yang, Ludovica Ciampi, Violeta Beltran-Sastre, Antonio Torres-Méndez, Manuel Irimia, Martin H Schaefer, Luis Serrano
Published 2021-02-01

Adding protein context to the human protein-protein interaction network to reveal meaningful interactions.

by Martin H Schaefer, Tiago J S Lopes, Nancy Mah, Jason E Shoemaker, Yukiko Matsuoka, Jean-Fred Fontaine, Caroline Louis-Jeune, Amie J Eisfeld, Gabriele Neumann, Carol Perez-Iratxeta, Yoshihiro Kawaoka, Hiroaki Kitano, Miguel A Andrade-Navarro
Published 2013-01-01

Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1.

by Spyros Petrakis, Tamás Raskó, Jenny Russ, Ralf P Friedrich, Martin Stroedicke, Sean-Patrick Riechers, Katja Muehlenberg, Angeli Möller, Anita Reinhardt, Arunachalam Vinayagam, Martin H Schaefer, Michael Boutros, Hervé Tricoire, Miguel A Andrade-Navarro, Erich E Wanker
Published 2012-01-01

Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.

by Apichat Suratanee, Martin H Schaefer, Matthew J Betts, Zita Soons, Heiko Mannsperger, Nathalie Harder, Marcus Oswald, Markus Gipp, Ellen Ramminger, Guillermo Marcus, Reinhard Männer, Karl Rohr, Erich Wanker, Robert B Russell, Robert B Russell, Miguel A Andrade-Navarro, Roland Eils, Rainer König
Published 2014-09-01