Toward personalized TGFβ inhibition for pancreatic cancer

by Ryan M Carr, Martin E Fernandez‐Zapico
Published 2019-11-01

New Aspects of the Epigenetics of Pancreatic Carcinogenesis

by Murat Toruner, Martin E. Fernandez-Zapico, Christopher L. Pin
Published 2020-08-01

Hedgehog/GLI Signaling Pathway: Transduction, Regulation, and Implications for Disease

by Ashley N. Sigafoos, Brooke D. Paradise, Martin E. Fernandez-Zapico
Published 2021-07-01

Recent Advances in the Clinical Targeting of Hedgehog/GLI Signaling in Cancer

by Hao Xie, Brooke D. Paradise, Wen Wee Ma, Martin E. Fernandez-Zapico
Published 2019-04-01

Back to the drawing board: Re-thinking the role of GLI1 in pancreatic carcinogenesis [version 2; referees: 3 approved]

by Tara L. Hogenson, Matthias Lauth, Marina Pasca diMagliano, Martin E. Fernandez-Zapico
Published 2016-06-01

The International Journal of Medical Students, a Platform for Medical Student Research Worldwide

by Juliana Bonilla-Velez, Americo Peña-Oscuvilca, Ilyas Sahin, Whitney S. Cordoba-Grueso, Martin E. Fernandez-Zapico
Published 2013-04-01

The International Journal of Medical Students, a Platform for Medical Student Research Worldwide

by Juliana Bonilla-Velez, Americo Peña-Oscuvilca, Ilyas Sahin, Whitney S. Cordoba-Grueso, Martin E. Fernandez-Zapico
Published 2013-11-01

Induction of Lysosome‐associated Protein Transmembrane 4 Beta via Sulfatase 2 Enhances Autophagic Flux in Liver Cancer Cells

by Yeonjung Ha, Yong Fang, Paola A. Romecin Duran, Ezequiel J. Tolosa, Catherine D. Moser, Martin E. Fernandez‐Zapico, Lewis R. Roberts
Published 2019-11-01

Hedgehog Signaling Overcomes an EZH2-Dependent Epigenetic Barrier to Promote Cholangiocyte Expansion.

by Nidhi Jalan-Sakrikar, Thiago M De Assuncao, Jie Lu, Luciana L Almada, Gwen Lomberk, Martin E Fernandez-Zapico, Raul Urrutia, Robert C Huebert
Published 2016-01-01

Hedgehog inhibition promotes a switch from Type II to Type I cell death receptor signaling in cancer cells.

by Satoshi Kurita, Justin L Mott, Sophie C Cazanave, Christian D Fingas, Maria E Guicciardi, Steve F Bronk, Lewis R Roberts, Martin E Fernandez-Zapico, Gregory J Gores
Published 2011-03-01

Cancer imaging and therapy utilizing a novel NIS-expressing adenovirus: The role of adenovirus death protein deletion

by Matthew Glen Robertson, Benjamin Bruce Eidenschink, Eriko Iguchi, Stanislav O. Zakharkin, Christopher J. LaRocca, Ezequiel J. Tolosa, Mark J. Truty, Kari Jacobsen, Martin E. Fernandez-Zapico, Julia Davydova
Published 2021-03-01

ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL

by Silvia Pietrobono, Giulia Anichini, Cesare Sala, Fabrizio Manetti, Luciana L. Almada, Sara Pepe, Ryan M. Carr, Brooke D. Paradise, Jann N. Sarkaria, Jaime I. Davila, Lorenzo Tofani, Ilaria Battisti, Giorgio Arrigoni, Li Ying, Cheng Zhang, Hu Li, Alexander Meves, Martin E. Fernandez-Zapico, Barbara Stecca
Published 2020-11-01

The transcription factor GLI1 mediates TGFβ1 driven EMT in hepatocellular carcinoma via a SNAI1-dependent mechanism.

by Xin Zheng, Natalia B Rumie Vittar, Xiaohong Gai, Maite G Fernandez-Barrena, Catherine D Moser, Chunling Hu, Luciana L Almada, Angela L McCleary-Wheeler, Sherine F Elsawa, Anne M Vrabel, Abdirashid M Shire, Andrea Comba, Snorri S Thorgeirsson, Youngsoo Kim, Qingguang Liu, Martin E Fernandez-Zapico, Lewis R Roberts
Published 2012-01-01

Derivation of adult canine intestinal organoids for translational research in gastroenterology

by Lawrance Chandra, Dana C. Borcherding, Dawn Kingsbury, Todd Atherly, Yoko M. Ambrosini, Agnes Bourgois-Mochel, Wang Yuan, Michael Kimber, Yijun Qi, Qun Wang, Michael Wannemuehler, N. Matthew Ellinwood, Elizabeth Snella, Martin Martin, Melissa Skala, David Meyerholz, Mary Estes, Martin E. Fernandez-Zapico, Albert E. Jergens, Jonathan P. Mochel, Karin Allenspach
Published 2019-04-01

LPCAT1-TERT fusions are uniquely recurrent in epithelioid trophoblastic tumors and positively regulate cell growth.

by Gavin R Oliver, Sofia Marcano-Bonilla, Jonathan Quist, Ezequiel J Tolosa, Eriko Iguchi, Amy A Swanson, Nicole L Hoppman, Tanya Schwab, Ashley Sigafoos, Naresh Prodduturi, Jesse S Voss, Shannon M Knight, Jin Zhang, Numrah Fadra, Raul Urrutia, Michael Zimmerman, Jan B Egan, Anthony G Bilyeu, Jin Jen, Ema Veras, Rema'a Al-Safi, Matthew Block, Sarah Kerr, Martin E Fernandez-Zapico, John K Schoolmeester, Eric W Klee
Published 2021-01-01

Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation

by Marion Maurel, Joanna Obacz, Tony Avril, Yong‐Ping Ding, Olga Papadodima, Xavier Treton, Fanny Daniel, Eleftherios Pilalis, Johanna Hörberg, Wenyang Hou, Marie‐Claude Beauchamp, Julien Tourneur‐Marsille, Dominique Cazals‐Hatem, Lucia Sommerova, Afshin Samali, Jan Tavernier, Roman Hrstka, Aurélien Dupont, Delphine Fessart, Frédéric Delom, Martin E Fernandez‐Zapico, Gregor Jansen, Leif A Eriksson, David Y Thomas, Loydie Jerome‐Majewska, Ted Hupp, Aristotelis Chatziioannou, Eric Chevet, Eric Ogier‐Denis
Published 2019-06-01

RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis

by Ryan M. Carr, Denis Vorobyev, Terra Lasho, David L. Marks, Ezequiel J. Tolosa, Alexis Vedder, Luciana L. Almada, Andrey Yurcheko, Ismael Padioleau, Bonnie Alver, Giacomo Coltro, Moritz Binder, Stephanie L. Safgren, Isaac Horn, Xiaona You, Eric Solary, Maria E. Balasis, Kurt Berger, James Hiebert, Thomas Witzig, Ajinkya Buradkar, Temeida Graf, Peter Valent, Abhishek A. Mangaonkar, Keith D. Robertson, Matthew T. Howard, Scott H. Kaufmann, Christopher Pin, Martin E. Fernandez-Zapico, Klaus Geissler, Nathalie Droin, Eric Padron, Jing Zhang, Sergey Nikolaev, Mrinal M. Patnaik
Published 2021-05-01