Computer Simulation Humans computer simulation controlled study human Adenosine Diphosphate Anticoagulants Aortic Valve Aortic valve Aortic valve fluid-structure interaction Aortic valve mechanic Aortic valve mechanics Aortic valve modeling Aortic valves Article Blood Coagulation Blood Platelets Blood vessels Computational Biology Coronary Vessels Fluid structure interaction Fluid-structure interaction Heart valve modeling Heart valves Immersed boundary method Immersed boundary methods Models, Cardiovascular Morphology Mucocutaneous Lymph Node Syndrome Physiological models