HIV-1 envelope resistance to proteasomal cleavage: implications for vaccine induced immune responses.

by Nicholas J Steers, Silvia Ratto-Kim, Mark S de Souza, Jeffrey R Currier, Jerome H Kim, Nelson L Michael, Carl R Alving, Mangala Rao
Published 2012-01-01

Reference ranges for the clinical laboratory derived from a rural population in Kericho, Kenya.

by Rukia S Kibaya, Christian T Bautista, Frederick K Sawe, Douglas N Shaffer, Warren B Sateren, Paul T Scott, Nelson L Michael, Merlin L Robb, Deborah L Birx, Mark S de Souza
Published 2008-01-01

Sex and Urbanicity Contribute to Variation in Lymphocyte Distribution across Ugandan Populations.

by Prossy Naluyima, Leigh Anne Eller, Benson J Ouma, Denis Kyabaggu, Peter Kataaha, David Guwatudde, Hannah Kibuuka, Fred Wabwire-Mangen, Merlin L Robb, Nelson L Michael, Mark S de Souza, Johan K Sandberg, Michael A Eller
Published 2016-01-01

Reference intervals in healthy adult Ugandan blood donors and their impact on conducting international vaccine trials.

by Leigh Anne Eller, Michael A Eller, Benson Ouma, Peter Kataaha, Denis Kyabaggu, Richard Tumusiime, Joseph Wandege, Ronald Sanya, Warren B Sateren, Fred Wabwire-Mangen, Hannah Kibuuka, Merlin L Robb, Nelson L Michael, Mark S de Souza
Published 2008-01-01

Phase I safety and immunogenicity evaluation of MVA-CMDR, a multigenic, recombinant modified vaccinia Ankara-HIV-1 vaccine candidate.

by Jeffrey R Currier, Viseth Ngauy, Mark S de Souza, Silvia Ratto-Kim, Josephine H Cox, Victoria R Polonis, Patricia Earl, Bernard Moss, Sheila Peel, Bonnie Slike, Somchai Sriplienchan, Prasert Thongcharoen, Robert M Paris, Merlin L Robb, Jerome Kim, Nelson L Michael, Mary A Marovich
Published 2010-11-01

Identification of immunodominant CD4-restricted epitopes co-located with antibody binding sites in individuals vaccinated with ALVAC-HIV and AIDSVAX B/E.

by Silvia Ratto-Kim, Mark S de Souza, Jeffrey R Currier, Nicos Karasavvas, John Sidney, Morgane Rolland, Anais Valencia-Micolta, Sirinan Madnote, Alessandro Sette, Sorachai Nitayaphan, Punnee Pitisuttuthum, Jaranit Kaewkungwal, Supachai Rerks-Ngarm, Robert O'Connell, Nelson Michael, Merlin L Robb, Mary Marovich, Jerome H Kim
Published 2015-01-01

Characterization of HIV-1 gp120 antibody specificities induced in anogenital secretions of RV144 vaccine recipients after late boost immunizations.

by Siriwat Akapirat, Chitraporn Karnasuta, Sandhya Vasan, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sirinan Madnote, Hathairat Savadsuk, Surawach Rittiroongrad, Jiraporn Puangkaew, Sanjay Phogat, James Tartaglia, Faruk Sinangil, Mark S de Souza, Jean-Louis Excler, Jerome H Kim, Merlin L Robb, Nelson L Michael, Viseth Ngauy, Robert J O'Connell, Nicos Karasavvas, RV305 Study Group
Published 2018-01-01

Vaccine-induced Human Antibodies Specific for the Third Variable Region of HIV-1 gp120 Impose Immune Pressure on Infecting Viruses

by Susan Zolla-Pazner, Paul T. Edlefsen, Morgane Rolland, Xiang-Peng Kong, Allan deCamp, Raphael Gottardo, Constance Williams, Sodsai Tovanabutra, Sandra Sharpe-Cohen, James I. Mullins, Mark S. deSouza, Nicos Karasavvas, Sorachai Nitayaphan, Supachai Rerks-Ngarm, Punnee Pitisuttihum, Jaranit Kaewkungwal, Robert J. O'Connell, Merlin L. Robb, Nelson L. Michael, Jerome H. Kim, Peter Gilbert
Published 2014-11-01

Innate and adaptive immune responses both contribute to pathological CD4 T cell activation in HIV-1 infected Ugandans.

by Michael A Eller, Kim G Blom, Veronica D Gonzalez, Leigh Anne Eller, Prossy Naluyima, Oliver Laeyendecker, Thomas C Quinn, Noah Kiwanuka, David Serwadda, Nelson K Sewankambo, Boonrat Tasseneetrithep, Maria J Wawer, Ronald H Gray, Mary A Marovich, Nelson L Michael, Mark S de Souza, Fred Wabwire-Mangen, Merlin L Robb, Jeffrey R Currier, Johan K Sandberg
Published 2011-04-01

CD8 and CD4 epitope predictions in RV144: no strong evidence of a T-cell driven sieve effect in HIV-1 breakthrough sequences from trial participants.

by Kalpana Dommaraju, Gustavo Kijak, Jonathan M Carlson, Brendan B Larsen, Sodsai Tovanabutra, Dan E Geraghty, Wenjie Deng, Brandon S Maust, Paul T Edlefsen, Eric Sanders-Buell, Silvia Ratto-Kim, Mark S deSouza, Supachai Rerks-Ngarm, Sorachai Nitayaphan, Punnee Pitisuttihum, Jaranit Kaewkungwal, Robert J O'Connell, Merlin L Robb, Nelson L Michael, James I Mullins, Jerome H Kim, Morgane Rolland
Published 2014-01-01

A randomized trial of vorinostat with treatment interruption after initiating antiretroviral therapy during acute HIV-1 infection

by Eugène D.M.B. Kroon, Jintanat Ananworanich, Amélie Pagliuzza, Ajantha Rhodes, Nittaya Phanuphak, Lydie Trautmann, Julie L. Mitchell, Michelle Chintanaphol, Jintana Intasan, Suteeraporn Pinyakorn, Khuntalee Benjapornpong, J. Judy Chang, Donn J. Colby, Nitiya Chomchey, James L.K. Fletcher, Keith Eubanks, Hua Yang, John Kapson, Ashanti Dantanarayana, Surekha Tennakoon, Robert J. Gorelick, Frank Maldarelli, Merlin L. Robb, Jerome H. Kim, Serena Spudich, Nicolas Chomont, Praphan Phanuphak, Sharon R. Lewin, Mark S. de Souza
Published 2020-09-01

Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation.

by Alexandra Schuetz, Claire Deleage, Irini Sereti, Rungsun Rerknimitr, Nittaya Phanuphak, Yuwadee Phuang-Ngern, Jacob D Estes, Netanya G Sandler, Suchada Sukhumvittaya, Mary Marovich, Surat Jongrakthaitae, Siriwat Akapirat, James L K Fletscher, Eugene Kroon, Robin Dewar, Rapee Trichavaroj, Nitiya Chomchey, Daniel C Douek, Robert J O Connell, Viseth Ngauy, Merlin L Robb, Praphan Phanuphak, Nelson L Michael, Jean-Louis Excler, Jerome H Kim, Mark S de Souza, Jintanat Ananworanich, RV254/SEARCH 010 and RV304/SEARCH 013 Study Groups
Published 2014-12-01