Simultaneous identification of multiple driver pathways in cancer.

by Mark D M Leiserson, Dima Blokh, Roded Sharan, Benjamin J Raphael
Published 2013-01-01

A Sticky Multinomial Mixture Model of Strand-Coordinated Mutational Processes in Cancer

by Itay Sason, Damian Wojtowicz, Welles Robinson, Mark D.M. Leiserson, Teresa M. Przytycka, Roded Sharan
Published 2020-03-01

Hidden Markov models lead to higher resolution maps of mutation signature activity in cancer

by Damian Wojtowicz, Itay Sason, Xiaoqing Huang, Yoo-Ah Kim, Mark D. M. Leiserson, Teresa M. Przytycka, Roded Sharan
Published 2019-07-01

Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer

by Yoo-Ah Kim, Damian Wojtowicz, Rebecca Sarto Basso, Itay Sason, Welles Robinson, Dorit S. Hochbaum, Mark D. M. Leiserson, Roded Sharan, Fabio Vadin, Teresa M. Przytycka
Published 2020-05-01

A multifactorial model of T cell expansion and durable clinical benefit in response to a PD-L1 inhibitor.

by Mark D M Leiserson, Vasilis Syrgkanis, Amy Gilson, Miroslav Dudik, Sharon Gillett, Jennifer Chayes, Christian Borgs, Dean F Bajorin, Jonathan E Rosenberg, Samuel Funt, Alexandra Snyder, Lester Mackey
Published 2018-01-01