T cell LFA-1 engagement induces HuR-dependent cytokine mRNA stabilization through a Vav-1, Rac1/2, p38MAPK and MKK3 signaling cascade.

by Vinod S Ramgolam, Scott D DeGregorio, Gautham K Rao, Mark Collinge, Sharmila S Subaran, Silva Markovic-Plese, Ruggero Pardi, Jeffrey R Bender
Published 2010-12-01

T cell LFA-1-induced proinflammatory mRNA stabilization is mediated by the p38 pathway kinase MK2 in a process regulated by hnRNPs C, H1 and K.

by Gautham K Rao, Albert Wong, Mark Collinge, Joseph Sarhan, Timur O Yarovinsky, Vinod S Ramgolam, Matthias Gaestel, Ruggero Pardi, Jeffrey R Bender
Published 2018-01-01

Cross-company evaluation of the human lymphocyte activation assay

by Mark Collinge, Patricia Schneider, Dingzhou Li, Stanley Parish, Carolyne Dumont, Wendy Freebern, Joseph Ghanime, Fanny Guimont-Derochers, Anja Langenkamp, Jose Lebron, Nianyu Li, Celine Marban, Lisa Plitnick, Jennifer Wheeler
Published 2020-01-01