Arylamine N-acetyltransferase 2 genotype-dependent N-acetylation of isoniazid in cryopreserved human hepatocytes

by Mark A. Doll, Raúl A. Salazar-González, Srineil Bodduluri, David W. Hein
Published 2017-07-01

UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target

by Kumar Saurabh, Parag P. Shah, Mark A. Doll, Leah J. Siskind, Levi J. Beverly
Published 2020-08-01

N-Acetyltransferase 1 Knockout Elevates Acetyl Coenzyme A Levels and Reduces Anchorage-Independent Growth in Human Breast Cancer Cell Lines

by Marcus W. Stepp, Raúl A. Salazar-González, Kyung U. Hong, Mark A. Doll, David W. Hein
Published 2019-01-01

Congenic rats with higher arylamine N-acetyltransferase 2 activity exhibit greater carcinogen-induced mammary tumor susceptibility independent of carcinogen metabolism

by Marcus W. Stepp, Mark A. Doll, David J. Samuelson, Mary Ann G. Sanders, J. Christopher States, David W. Hein
Published 2017-03-01

Acetylator Genotype-Dependent Dyslipidemia in Rats Congenic for N-Acetyltransferase 2

by Kyung U. Hong, Mark A. Doll, Angeliki Lykoudi, Raúl A. Salazar-González, Mariam R. Habil, Kennedy M. Walls, Alaa F. Bakr, Smita S. Ghare, Shirish S. Barve, Gavin E. Arteel, David W. Hein
Published 2020-01-01

Na/H Exchange Regulatory Factor 1 Deficient Mice Show Evidence of Oxidative Stress and Altered Cisplatin Pharmacokinetics

by Adrienne M. Bushau-Sprinkle, Michelle T. Barati, Yuxuan Zheng, Walter H. Watson, Kenneth B. Gagnon, Syed Jalal Khundmiri, Kathleen T. Kitterman, Barbara J. Clark, Leah J. Siskind, Mark A. Doll, Michael E. Brier, Susan Coventry, Eleanor D. Lederer
Published 2021-06-01

Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury

by Tess V. Dupre, Mark A. Doll, Parag P. Shah, Cierra N. Sharp, Deanna Siow, Judit Megyesi, James Shayman, Alicja Bielawska, Jacek Bielawski, Levi J. Beverly, Maria Hernandez-Corbacho, Christopher J. Clarke, Ashley J. Snider, Rick G. Schnellmann, Lina M. Obeid, Yusuf A. Hannun, Leah J. Siskind
Published 2017-07-01