The Mitochondrial Unfolded Protein Response: A Hinge Between Healthy and Pathological Aging

by Francisco Muñoz-Carvajal, Francisco Muñoz-Carvajal, Francisco Muñoz-Carvajal, Mario Sanhueza, Mario Sanhueza
Published 2020-09-01

Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders

by Natalia Salvadores, Natalia Salvadores, Mario Sanhueza, Mario Sanhueza, Patricio Manque, Felipe A. Court, Felipe A. Court
Published 2017-09-01

Gain-of-function mutations in the ALS8 causative gene VAPB have detrimental effects on neurons and muscles

by Mario Sanhueza, Luigi Zechini, Trudy Gillespie, Giuseppa Pennetta
Published 2013-12-01

Filtering of Data-Driven Gene Regulatory Networks Using Drosophila melanogaster as a Case Study

by Yesid Cuesta-Astroz, Guilherme Gischkow Rucatti, Leandro Murgas, Leandro Murgas, Carol D. SanMartín, Carol D. SanMartín, Mario Sanhueza, Mario Sanhueza, Alberto J. M. Martin, Alberto J. M. Martin
Published 2021-07-01

Network analyses reveal novel aspects of ALS pathogenesis.

by Mario Sanhueza, Andrea Chai, Colin Smith, Brett A McCray, T Ian Simpson, J Paul Taylor, Giuseppa Pennetta
Published 2015-03-01

Mitochondria and Calcium Regulation as Basis of Neurodegeneration Associated With Aging

by Marioly Müller, Marioly Müller, Ulises Ahumada-Castro, Mario Sanhueza, Christian Gonzalez-Billault, Christian Gonzalez-Billault, Christian Gonzalez-Billault, Felipe A. Court, Felipe A. Court, Felipe A. Court, César Cárdenas, César Cárdenas, César Cárdenas, César Cárdenas
Published 2018-07-01

A genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's disease.

by John P Miller, Bridget E Yates, Ismael Al-Ramahi, Ari E Berman, Mario Sanhueza, Eugene Kim, Maria de Haro, Francesco DeGiacomo, Cameron Torcassi, Jennifer Holcomb, Juliette Gafni, Sean D Mooney, Juan Botas, Lisa M Ellerby, Robert E Hughes
Published 2012-01-01