Thermal Stability Threshold for Amyloid Formation in Light Chain Amyloidosis

by Tanya L. Poshusta, Nagaaki Katoh, Morie A. Gertz, Angela Dispenzieri, Marina Ramirez-Alvarado
Published 2013-11-01

Mutations in specific structural regions of immunoglobulin light chains are associated with free light chain levels in patients with AL amyloidosis.

by Tanya L Poshusta, Laura A Sikkink, Nelson Leung, Raynell J Clark, Angela Dispenzieri, Marina Ramirez-Alvarado
Published 2009-01-01

Immunoglobulin Light Chains Form an Extensive and Highly Ordered Fibril Involving the N- and C-Termini

by Dennis W. Piehl, Luis M. Blancas-Mejía, Jonathan S. Wall, Stephen J. Kennel, Marina Ramirez-Alvarado, Chad M. Rienstra
Published 2017-02-01

Differences in immunoglobulin light chain species found in urinary exosomes in light chain amyloidosis (Al).

by Marina Ramirez-Alvarado, Christopher J Ward, Bing Q Huang, Xun Gong, Marie C Hogan, Benjamin J Madden, M Cristine Charlesworth, Nelson Leung
Published 2012-01-01

Differential recruitment efficacy of patient-derived amyloidogenic and myeloma light chain proteins by synthetic fibrils-A metric for predicting amyloid propensity.

by Emily B Martin, Angela Williams, Craig Wooliver, R Eric Heidel, Sarah Adams, John Dunlap, Marina Ramirez-Alvarado, Luis M Blancas-Mejia, Ronald H Lands, Stephen J Kennel, Jonathan S Wall
Published 2017-01-01

Light Chain Amyloid Fibrils Cause Metabolic Dysfunction in Human Cardiomyocytes.

by Helen P McWilliams-Koeppen, James S Foster, Nicole Hackenbrack, Marina Ramirez-Alvarado, Dallas Donohoe, Angela Williams, Sallie Macy, Craig Wooliver, Dale Wortham, Jennifer Morrell-Falvey, Carmen M Foster, Stephen J Kennel, Jonathan S Wall
Published 2015-01-01