Activation of EGFR/ERBB2 via pathways involving ERK1/2, P38 MAPK, AKT and FOXO enhances recovery of diabetic hearts from ischemia-reperfusion injury.

by Saghir Akhtar, Mariam H M Yousif, Bindu Chandrasekhar, Ibrahim F Benter
Published 2012-01-01

Chronic Treatment with Ang-(1-7) Reverses Abnormal Reactivity in the Corpus Cavernosum and Normalizes Diabetes-Induced Changes in the Protein Levels of ACE, ACE2, ROCK1, ROCK2 and...

by Mariam H. M. Yousif, Batoul Makki, Ahmed Z. El-Hashim, Saghir Akhtar, Ibrahim F. Benter
Published 2014-01-01

Transactivation of ErbB Family of Receptor Tyrosine Kinases Is Inhibited by Angiotensin-(1-7) via Its Mas Receptor.

by Saghir Akhtar, Bindu Chandrasekhar, Sreeja Attur, Gursev S Dhaunsi, Mariam H M Yousif, Ibrahim F Benter
Published 2015-01-01

Activation of ErbB2 and Downstream Signalling via Rho Kinases and ERK1/2 Contributes to Diabetes-Induced Vascular Dysfunction.

by Saghir Akhtar, Mariam H M Yousif, Gursev S Dhaunsi, Fatma Sarkhouh, Bindu Chandrasekhar, Sreeja Attur, Ibrahim F Benter
Published 2013-01-01

Cationic Polyamidoamine Dendrimers as Modulators of EGFR Signaling In Vitro and In Vivo.

by Saghir Akhtar, Bashayer Al-Zaid, Ahmed Z El-Hashim, Bindu Chandrasekhar, Sreeja Attur, Mariam H M Yousif, Ibrahim F Benter
Published 2015-01-01