Purinergic Receptors on Oligodendrocyte Progenitors: Promising Targets for Myelin Repair in Multiple Sclerosis?

by Davide Lecca, Maria P. Abbracchio, Marta Fumagalli
Published 2021-01-01

Pathophysiological Role of Purines and Pyrimidines in Neurodevelopment: Unveiling New Pharmacological Approaches to Congenital Brain Diseases

by Marta Fumagalli, Davide Lecca, Maria P. Abbracchio, Stefania Ceruti
Published 2017-12-01

The Distribution of GPR17-Expressing Cells Correlates with White Matter Inflammation Status in Brain Tissues of Multiple Sclerosis Patients

by Jacopo Angelini, Davide Marangon, Stefano Raffaele, Davide Lecca, Maria P. Abbracchio
Published 2021-04-01

A Rapid and Efficient Immunoenzymatic Assay to Detect Receptor Protein Interactions: G Protein-Coupled Receptors

by Elisa Zappelli, Simona Daniele, Maria P. Abbracchio, Claudia Martini, Maria Letizia Trincavelli
Published 2014-04-01

Abnormal Upregulation of GPR17 Receptor Contributes to Oligodendrocyte Dysfunction in SOD1 G93A Mice

by Elisabetta Bonfanti, Tiziana Bonifacino, Stefano Raffaele, Marco Milanese, Erica Morgante, Giambattista Bonanno, Maria P. Abbracchio, Marta Fumagalli
Published 2020-03-01

Purple Corn Extract as Anti-allodynic Treatment for Trigeminal Pain: Role of Microglia

by Giulia Magni, Alessandra Marinelli, Daniele Riccio, Davide Lecca, Chiara Tonelli, Maria P. Abbracchio, Katia Petroni, Stefania Ceruti
Published 2018-11-01

Early and transient alteration of adenosine A2A receptor signaling in a mouse model of Huntington disease

by Alessia Tarditi, Alessandra Camurri, Katia Varani, Pier Andrea Borea, Ben Woodman, Gillian Bates, Elena Cattaneo, Maria P. Abbracchio
Published 2006-07-01

Development of the first in vivo GPR17 ligand through an iterative drug discovery pipeline: A novel disease-modifying strategy for multiple sclerosis.

by Chiara Parravicini, Davide Lecca, Davide Marangon, Giusy Tindara Coppolino, Simona Daniele, Elisabetta Bonfanti, Marta Fumagalli, Luca Raveglia, Claudia Martini, Elisabetta Gianazza, Maria Letizia Trincavelli, Maria P Abbracchio, Ivano Eberini
Published 2020-01-01

Surface Plasmon Resonance as a Tool for Ligand Binding Investigation of Engineered GPR17 Receptor, a G Protein Coupled Receptor Involved in Myelination

by Davide Capelli, Chiara Parravicini, Giorgio Pochetti, Roberta Montanari, Caterina Temporini, Marco Rabuffetti, Maria Letizia Trincavelli, Simona Daniele, Marta Fumagalli, Simona Saporiti, Elisabetta Bonfanti, Maria P. Abbracchio, Ivano Eberini, Stefania Ceruti, Enrica Calleri, Stefano Capaldi
Published 2020-01-01

The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair.

by Davide Lecca, Maria Letizia Trincavelli, Paolo Gelosa, Luigi Sironi, Paolo Ciana, Marta Fumagalli, Giovanni Villa, Claudia Verderio, Carlotta Grumelli, Uliano Guerrini, Elena Tremoli, Patrizia Rosa, Serena Cuboni, Claudia Martini, Annalisa Buffo, Mauro Cimino, Maria P Abbracchio
Published 2008-01-01