A machine learning and network framework to discover new indications for small molecules.

by Coryandar Gilvary, Jamal Elkhader, Neel Madhukar, Claire Henchcliffe, Marcus D Goncalves, Olivier Elemento
Published 2020-08-01

Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition.

by Marcus D Goncalves, Emidio E Pistilli, Anthony Balduzzi, Morris J Birnbaum, Jennifer Lachey, Tejvir S Khurana, Rexford S Ahima
Published 2010-09-01

Rac-Mediated Macropinocytosis of Extracellular Protein Promotes Glucose Independence in Non-Small Cell Lung Cancer

by Cindy Hodakoski, Benjamin D. Hopkins, Guoan Zhang, Taojunfeng Su, Zhe Cheng, Roxanne Morris, Kyu Y. Rhee, Marcus D. Goncalves, Lewis C. Cantley
Published 2019-01-01

GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase

by Roger J. Liang, Samuel Taylor, Navid Nahiyaan, Junho Song, Charles J. Murphy, Ezequiel Dantas, Shuyuan Cheng, Ting-Wei Hsu, Shakti Ramsamooj, Rahul Grover, Seo-Kyoung Hwang, Bryan Ngo, Lewis C. Cantley, Kyu Y. Rhee, Marcus D. Goncalves
Published 2021-03-01

Treating Alpelisib-Induced Hyperglycemia with Very Low Carbohydrate Diets and Sodium-Glucose Co-Transporter 2 Inhibitors: A Case Series

by Tahj Blow BS, Parker N. Hyde PhD, John N. Falcone MD, Aaron Neinstein MD, Neil Vasan MD, PhD, Ritika Chitkara MPAS, Maurice A. Hurd BA, Sagar Sardesai MBBS, Maryam B. Lustberg MD, MPH, James H. Flory MD, MSCE, Jeff S. Volek PhD, Marcus D. Goncalves MD, PhD
Published 2021-07-01