An Sp1/Sp3 binding polymorphism confers methylation protection.

by Yanis A Boumber, Yutaka Kondo, Xuqi Chen, Lanlan Shen, Yi Guo, Carmen Tellez, Marcos R H Estécio, Saira Ahmed, Jean-Pierre J Issa
Published 2008-08-01

Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia.

by Jaroslav Jelinek, Vazganush Gharibyan, Marcos R H Estecio, Kimie Kondo, Rong He, Woonbok Chung, Yue Lu, Nianxiang Zhang, Shoudan Liang, Hagop M Kantarjian, Jorge E Cortes, Jean-Pierre J Issa
Published 2011-01-01

LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability.

by Marcos R H Estécio, Vazganush Gharibyan, Lanlan Shen, Ashraf E K Ibrahim, Ketan Doshi, Rong He, Jaroslav Jelinek, Allen S Yang, Pearlly S Yan, Tim H-M Huang, Eloiza H Tajara, Jean-Pierre J Issa
Published 2007-05-01

Frequent alteration of MLL3 frameshift mutations in microsatellite deficient colorectal cancer.

by Yoshiyuki Watanabe, Ryan J Castoro, Hyun Soo Kim, Brittany North, Ritsuko Oikawa, Tetsuya Hiraishi, Saira S Ahmed, Woonbok Chung, Mee-Yon Cho, Minoru Toyota, Fumio Itoh, Marcos R H Estecio, Lanlan Shen, Jaroslav Jelinek, Jean-Pierre J Issa
Published 2011-01-01