The bone is the major source of high circulating intact fibroblast growth factor-23 in acute murine polymicrobial sepsis induced by cecum ligation puncture.

by Jessica Bayer, Ravikumar Vaghela, Susanne Drechsler, Marcin F Osuchowski, Reinhold G Erben, Olena Andrukhova
Published 2021-01-01

An Early Myelosuppression in the Acute Mouse Sepsis Is Partly Outcome-Dependent

by Tomasz Skirecki, Susanne Drechsler, Aldona Jeznach, Grażyna Hoser, Mohammad Jafarmadar, Jerzy Kawiak, Marcin F. Osuchowski
Published 2021-07-01

Experimentally Approaching the ICU: Monitoring Outcome-Based Responses in the Two-Hit Mouse Model of Posttraumatic Sepsis

by Susanne Drechsler, Katrin M. Weixelbaumer, Heinz Redl, Martijn van Griensven, Soheyl Bahrami, Marcin F. Osuchowski
Published 2011-01-01

Impact of Idarucizumab and Andexanet Alfa on DOAC Plasma Concentration and ClotPro^® Clotting Time: An Ex Vivo Spiking Study in A Cohort of Trauma Patients

by Daniel Oberladstätter, Christoph J. Schlimp, Johannes Zipperle, Marcin F. Osuchowski, Wolfgang Voelckel, Oliver Grottke, Herbert Schöchl
Published 2021-08-01

The Fluctuations of Leukocytes and Circulating Cytokines in Septic Humanized Mice Vary With Outcome

by Tomasz Skirecki, Susanne Drechsler, Grazyna Hoser, Mohammad Jafarmadar, Katarzyna Siennicka, Zygmunt Pojda, Jerzy Kawiak, Marcin F. Osuchowski
Published 2019-06-01

Mitochondria-Targeted Antioxidants SkQ1 and MitoTEMPO Failed to Exert a Long-Term Beneficial Effect in Murine Polymicrobial Sepsis

by Pia Rademann, Adelheid Weidinger, Susanne Drechsler, Andras Meszaros, Johannes Zipperle, Mohammad Jafarmadar, Sergiu Dumitrescu, Ara Hacobian, Luisa Ungelenk, Franziska Röstel, Jozsef Kaszaki, Andrea Szabo, Vladimir P. Skulachev, Michael Bauer, Soheyl Bahrami, Sebastian Weis, Andrey V. Kozlov, Marcin F. Osuchowski
Published 2017-01-01

Bridging animal and clinical research during SARS-CoV-2 pandemic: A new-old challenge

by Martin S. Winkler, Tomasz Skirecki, Frank M. Brunkhorst, Sara Cajander, Jean-Marc Cavaillon, Ricard Ferrer, Stefanie B. Flohé, Alberto García-Salido, Evangelos J. Giamarellos-Bourboulis, Massimo Girardis, Matthijs Kox, Gunnar Lachmann, Ignacio Martin-Loeches, Mihai G. Netea, Thibaud Spinetti, Joerg C. Schefold, Antoni Torres, Florian Uhle, Fabienne Venet, Sebastian Weis, André Scherag, Ignacio Rubio, Marcin F. Osuchowski
Published 2021-04-01

Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

by Marcin F. Osuchowski, Alfred Ayala, Soheyl Bahrami, Michael Bauer, Mihaly Boros, Jean-Marc Cavaillon, Irshad H. Chaudry, Craig M. Coopersmith, Clifford Deutschman, Susanne Drechsler, Philip Efron, Claes Frostell, Gerhard Fritsch, Waldemar Gozdzik, Judith Hellman, Markus Huber-Lang, Shigeaki Inoue, Sylvia Knapp, Andrey V. Kozlov, Claude Libert, John C. Marshall, Lyle L. Moldawer, Peter Radermacher, Heinz Redl, Daniel G. Remick, Mervyn Singer, Christoph Thiemermann, Ping Wang, Willem Joost Wiersinga, Xianzhong Xiao, Basilia Zingarelli
Published 2018-08-01