Age-associated motor and visuo-spatial learning phenotype in Dyrk1A heterozygous mutant mice

by Glòria Arqué, María Martínez de Lagrán, Maria L. Arbonés, Mara Dierssen
Published 2009-11-01

Impaired spatial learning strategies and novel object recognition in mice haploinsufficient for the dual specificity tyrosine-regulated kinase-1A (Dyrk1A).

by Glòria Arqué, Vassiliki Fotaki, David Fernández, María Martínez de Lagrán, Maria L Arbonés, Mara Dierssen
Published 2008-07-01

Overexpression of Dyrk1A is implicated in several cognitive, electrophysiological and neuromorphological alterations found in a mouse model of Down syndrome.

by Susana García-Cerro, Paula Martínez, Verónica Vidal, Andrea Corrales, Jesús Flórez, Rebeca Vidal, Noemí Rueda, María L Arbonés, Carmen Martínez-Cué
Published 2014-01-01

DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down Syndrome

by Sònia Najas, Juan Arranz, Pamela A. Lochhead, Anne L. Ashford, David Oxley, Jean M. Delabar, Simon J. Cook, María José Barallobre, Maria L. Arbonés
Published 2015-02-01

DYRK1A Kinase Positively Regulates Angiogenic Responses in Endothelial Cells

by Esteban J. Rozen, Julia Roewenstrunk, María José Barallobre, Chiara Di Vona, Carole Jung, Ana F. Figueiredo, Jeroni Luna, Cristina Fillat, Maria L. Arbonés, Mariona Graupera, Miguel A. Valverde, Susana de la Luna
Published 2018-05-01

Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome

by Juan Arranz, Elisa Balducci, Krisztina Arató, Gentzane Sánchez-Elexpuru, Sònia Najas, Alberto Parras, Elena Rebollo, Isabel Pijuan, Ionas Erb, Gaetano Verde, Ignasi Sahun, Maria J. Barallobre, José J. Lucas, Marina P. Sánchez, Susana de la Luna, Maria L. Arbonés
Published 2019-07-01