Dual-Target CAR-Ts with On- and Off-Tumour Activity May Override Immune Suppression in Solid Cancers: A Mathematical Proof of Concept

by Odelaisy León-Triana, Antonio Pérez-Martínez, Manuel Ramírez-Orellana, Víctor M. Pérez-García
Published 2021-02-01

A Mathematical Description of the Bone Marrow Dynamics during CAR T-Cell Therapy in B-Cell Childhood Acute Lymphoblastic Leukemia

by Álvaro Martínez-Rubio, Salvador Chulián, Cristina Blázquez Goñi, Manuel Ramírez Orellana, Antonio Pérez Martínez, Alfonso Navarro-Zapata, Cristina Ferreras, Victor M. Pérez-García, María Rosa
Published 2021-06-01

Mesenchymal stromal cells derived from the bone marrow of acute lymphoblastic leukemia patients show altered BMP4 production: correlations with the course of disease.

by Ángeles Vicente López, Miriam Nohemí Vázquez García, Gustavo J Melen, Ana Entrena Martínez, Isabel Cubillo Moreno, Javier García-Castro, Manuel Ramírez Orellana, Agustín Gregorio Zapata González
Published 2014-01-01

Increased Hypothalamic Anti-Inflammatory Mediators in Non-Diabetic Insulin Receptor Substrate 2-Deficient Mice

by María Vinaixa, Sandra Canelles, África González-Murillo, Vítor Ferreira, Diana Grajales, Santiago Guerra-Cantera, Ana Campillo-Calatayud, Manuel Ramírez-Orellana, Óscar Yanes, Laura M. Frago, Ángela M. Valverde, Vicente Barrios
Published 2021-08-01

The Netrin-4/Laminin γ1/Neogenin-1 complex mediates migration in SK-N-SH neuroblastoma cells

by Andrea A. Villanueva, Sofía Puvogel, Pablo Lois, Ernesto Muñoz-Palma, Manuel Ramírez Orellana, Fabiana Lubieniecki, Fernando Casco Claro, Iván Gallegos, Javier García-Castro, Pilar Sanchez-Gomez, Vicente A. Torres, Verónica Palma
Published 2019-01-01

High-Dimensional Analysis of Single-Cell Flow Cytometry Data Predicts Relapse in Childhood Acute Lymphoblastic Leukaemia

by Salvador Chulián, Álvaro Martínez-Rubio, Víctor M. Pérez-García, María Rosa, Cristina Blázquez Goñi, Juan Francisco Rodríguez Gutiérrez, Lourdes Hermosín-Ramos, Águeda Molinos Quintana, Teresa Caballero-Velázquez, Manuel Ramírez-Orellana, Ana Castillo Robleda, Juan Luis Fernández-Martínez
Published 2021-12-01

The Netrin-1-Neogenin-1 signaling axis controls neuroblastoma cell migration via integrin-β1 and focal adhesion kinase activation

by Andrea A. Villanueva, Pilar Sanchez-Gomez, Ernesto Muñoz-Palma, Sofía Puvogel, Bárbara S. Casas, Cecilia Arriagada, Isaac Peña-Villalobos, Pablo Lois, Manuel Ramírez Orellana, Fabiana Lubieniecki, Fernando Casco Claro, Iván Gallegos, Javier García-Castro, Vicente A. Torres, Verónica Palma
Published 2021-01-01

TYK2 Variants in B-Acute Lymphoblastic Leukaemia

by Edgar Turrubiartes-Martínez, Irene Bodega-Mayor, Pablo Delgado-Wicke, Francisca Molina-Jiménez, Diana Casique-Aguirre, Martín González-Andrade, Inmaculada Rapado, Mireia Camós, Cristina Díaz-de-Heredia, Eva Barragán, Manuel Ramírez-Orellana, Beatriz Aguado, Ángela Figuera, Joaquín Martínez-López, Elena Fernández-Ruiz
Published 2020-11-01

Measurable Residual Disease Assessed by Flow-Cytometry Is a Stable Prognostic Factor for Pediatric T-Cell Acute Lymphoblastic Leukemia in Consecutive SEHOP Protocols Whereas the Im...

by Nerea Vega-García, Nerea Vega-García, Sara Perez-Jaume, Elena Esperanza-Cebollada, Elena Esperanza-Cebollada, Clara Vicente-Garcés, Clara Vicente-Garcés, Montserrat Torrebadell, Montserrat Torrebadell, Montserrat Torrebadell, Antonio Jiménez-Velasco, Margarita Ortega, Marta Llop, Marta Llop, Lorea Abad, José Manuel Vagace, Alfredo Minguela, Marta Pratcorona, Joaquín Sánchez-Garcia, Clara B. García-Calderón, María Teresa Gómez-Casares, Estela Martín-Clavero, Adela Escudero, Marta Riñón Martinez-Gallo, Luz Muñoz, María Rosario Velasco, Marina García-Morin, Albert Català, Albert Català, Albert Català, Antonia Pascual, Pablo Velasco, José Mª. Fernández, Alvaro Lassaletta, José Luis Fuster, Isabel Badell, Águeda Molinos-Quintana, Antonio Molinés, Pilar Guerra-García, Pilar Guerra-García, Antonio Pérez-Martínez, Antonio Pérez-Martínez, Miriam García-Abós, Reyes Robles Ortiz, Sandra Pisa, Rosa Adán, Cristina Díaz de Heredia, José Luis Dapena, José Luis Dapena, Susana Rives, Susana Rives, Susana Rives, Manuel Ramírez-Orellana, Mireia Camós, Mireia Camós, Mireia Camós
Published 2021-02-01