Editorial: Pathophysiological Interrelationship Between Obesity, Metabolic Diseases, and Cancer

by Manuel D. Gahete, Manuel D. Gahete, Manuel D. Gahete, Manuel D. Gahete, Riccarda Granata, Raúl M. Luque, Raúl M. Luque, Raúl M. Luque, Raúl M. Luque
Published 2021-09-01

The Pituitary Gland is a Novel Major Site of Action of Metformin in Non-Human Primates: a Potential Path to Expand and Integrate Its Metabolic Actions

by Mari C. Vázquez-Borrego, Antonio C. Fuentes-Fayos, Manuel D. Gahete, Justo P. Castaño, Rhonda D. Kineman, Raúl M. Luque
Published 2018-09-01

Role of endogenous cortistatin in the regulation of ghrelin system expression at pancreatic level under normal and obese conditions.

by Belén Chanclón, Raúl M Luque, José Córdoba-Chacón, Manuel D Gahete, Ana I Pozo-Salas, Justo P Castaño, Francisco Gracia-Navarro, Antonio J Martínez-Fuentes
Published 2013-01-01

A novel human ghrelin variant (In1-ghrelin) and ghrelin-O-acyltransferase are overexpressed in breast cancer: potential pathophysiological relevance.

by Manuel D Gahete, José Córdoba-Chacón, Marta Hergueta-Redondo, Antonio J Martínez-Fuentes, Rhonda D Kineman, Gema Moreno-Bueno, Raúl M Luque, Justo P Castaño
Published 2011-01-01

Obesity alters gene expression for GH/IGF-I axis in mouse mammary fat pads: differential role of cortistatin and somatostatin.

by Alicia Villa-Osaba, Manuel D Gahete, José Córdoba-Chacón, Luis de Lecea, Ana I Pozo-Salas, Francisco Javier Delgado-Lista, Marina Álvarez-Benito, José López-Miranda, Raúl M Luque, Justo P Castaño
Published 2015-01-01

Dietary Intervention Modulates the Expression of Splicing Machinery in Cardiovascular Patients at High Risk of Type 2 Diabetes Development: From the CORDIOPREV Study

by Mercedes del Río-Moreno, Raúl M. Luque, Oriol A. Rangel-Zúñiga, Emilia Alors-Pérez, Juan F. Alcalá-Diaz, Irene Roncero-Ramos, Antonio Camargo, Manuel D. Gahete, José López-Miranda, Justo P. Castaño
Published 2020-11-01

The long non-coding RNA GHSROS reprograms prostate cancer cell lines toward a more aggressive phenotype

by Patrick B. Thomas, Penny Jeffery, Manuel D. Gahete, Eliza Whiteside, Carina Walpole, Michelle Maugham, Lidija Jovanovic, Jennifer Gunter, Elizabeth Williams, Colleen Nelson, Adrian Herington, Raul M. Luque, Rakesh Veedu, Lisa K. Chopin, Inge Seim
Published 2021-02-01

Changes in Splicing Machinery Components Influence, Precede, and Early Predict the Development of Type 2 Diabetes: From the CORDIOPREV StudyResearch in context

by Manuel D. Gahete, Mercedes del Rio-Moreno, Antonio Camargo, Juan F. Alcala-Diaz, Emilia Alors-Perez, Javier Delgado-Lista, Oscar Reyes, Sebastian Ventura, Pablo Perez-Martínez, Justo P. Castaño, José Lopez-Miranda, Raul M. Luque
Published 2018-11-01

Comparative Cytotoxic Activity of Hydroxytyrosol and Its Semisynthetic Lipophilic Derivatives in Prostate Cancer Cells

by Antonio J. León-González, Prudencio Sáez-Martínez, Juan M. Jiménez-Vacas, Vicente Herrero-Aguayo, Antonio J. Montero-Hidalgo, Enrique Gómez-Gómez, Andrés Madrona, Justo P. Castaño, José L. Espartero, Manuel D. Gahete, Raúl M. Luque
Published 2021-08-01

Unleashing the Diagnostic, Prognostic and Therapeutic Potential of the Neuronostatin/GPR107 System in Prostate Cancer

by Prudencio Sáez-Martínez, Juan M. Jiménez-Vacas, Antonio J. León-González, Vicente Herrero-Aguayo, Antonio J. Montero Hidalgo, Enrique Gómez-Gómez, Rafael Sánchez-Sánchez, María J. Requena-Tapia, Justo P. Castaño, Manuel D. Gahete, Raúl M. Luque
Published 2020-06-01

The truncated isoform of somatostatin receptor5 (sst5TMD4) is associated with poorly differentiated thyroid cancer.

by Manel Puig-Domingo, Raúl M Luque, Jordi L Reverter, Laura M López-Sánchez, Manuel D Gahete, Michael D Culler, Gonzalo Díaz-Soto, Francisco Lomeña, Mattia Squarcia, José Luis Mate, Mireia Mora, Laureano Fernández-Cruz, Oscar Vidal, Antonio Alastrué, Jose Balibrea, Irene Halperin, Dídac Mauricio, Justo P Castaño
Published 2014-01-01

Clinical Utility of Ghrelin-O-Acyltransferase (GOAT) Enzyme as a Diagnostic Tool and Potential Therapeutic Target in Prostate Cancer

by Juan M. Jiménez-Vacas, Enrique Gómez-Gómez, Antonio J. Montero-Hidalgo, Vicente Herrero-Aguayo, Fernando L-López, Rafael Sánchez-Sánchez, Ipek Guler, Ana Blanca, María José Méndez-Vidal, Julia Carrasco, José Lopez-Miranda, María J. Requena-Tapia, Justo P. Castaño, Manuel D. Gahete, Raúl M. Luque
Published 2019-11-01

Oncogenic Role of Secreted Engrailed Homeobox 2 (EN2) in Prostate Cancer

by Enrique Gómez-Gómez, Juan M. Jiménez-Vacas, Sergio Pedraza-Arévalo, Fernando López-López, Vicente Herrero-Aguayo, Daniel Hormaechea-Agulla, José Valero-Rosa, Alejandro Ibáñez-Costa, Antonio J. León-González, Rafael Sánchez-Sánchez, Teresa González-Serrano, Maria J. Requena-Tapia, Justo P. Castaño, Julia Carrasco-Valiente, Manuel D. Gahete, Raúl M. Luque
Published 2019-09-01

Splicing Machinery is Dysregulated in Pituitary Neuroendocrine Tumors and is Associated with Aggressiveness Features

by Mari C. Vázquez-Borrego, Antonio C. Fuentes-Fayos, Eva Venegas-Moreno, Esther Rivero-Cortés, Elena Dios, Paloma Moreno-Moreno, Ainara Madrazo-Atutxa, Pablo Remón, Juan Solivera, Luiz E. Wildemberg, Leandro Kasuki, Judith M. López-Fernández, Mônica R. Gadelha, María A. Gálvez-Moreno, Alfonso Soto-Moreno, Manuel D. Gahete, Justo P. Castaño, and Raúl M. Luque
Published 2019-09-01

The oncogenic role of the In1-ghrelin splicing variant in prostate cancer aggressiveness

by Daniel Hormaechea-Agulla, Manuel D. Gahete, Juan M. Jiménez-Vacas, Enrique Gómez-Gómez, Alejandro Ibáñez-Costa, Fernando L-López, Esther Rivero-Cortés, André Sarmento-Cabral, José Valero-Rosa, Julia Carrasco-Valiente, Rafael Sánchez-Sánchez, Rosa Ortega-Salas, María M. Moreno, Natia Tsomaia, Steve M. Swanson, Michael D. Culler, María J. Requena, Justo P. Castaño, Raúl M. Luque
Published 2017-08-01

Dysregulation of the splicing machinery is directly associated to aggressiveness of prostate cancer

by Juan M. Jiménez-Vacas, Vicente Herrero-Aguayo, Antonio J. Montero-Hidalgo, Enrique Gómez-Gómez, Antonio C. Fuentes-Fayos, Antonio J. León-González, Prudencio Sáez-Martínez, Emilia Alors-Pérez, Sergio Pedraza-Arévalo, Teresa González-Serrano, Oscar Reyes, Ana Martínez-López, Rafael Sánchez-Sánchez, Sebastián Ventura, Elena M. Yubero-Serrano, María J. Requena-Tapia, Justo P. Castaño, Manuel D. Gahete, Raúl M. Luque
Published 2020-01-01