Different liposomal amphotericin B formulations for visceral leishmaniasis

by Thomas P C Dorlo, Manica Balasegaram
Published 2014-08-01

More efficient ways of assessing treatments for neglected tropical diseases are required: innovative study designs, new endpoints, and markers of effects.

by Piero Olliaro, Michel T Vaillant, Shyam Sundar, Manica Balasegaram
Published 2012-01-01

Antimicrobial resistance – moving forward?

by Marta Lomazzi, Michael Moore, April Johnson, Manica Balasegaram, Bettina Borisch
Published 2019-07-01

Tackling antimicrobial resistance in neonatal sepsis

by Laura Folgori, Sally J Ellis, Julia A Bielicki, Paul T Heath, Mike Sharland, Manica Balasegaram
Published 2017-11-01

Cost-effectiveness analysis of combination therapies for visceral leishmaniasis in the Indian subcontinent.

by Filip Meheus, Manica Balasegaram, Piero Olliaro, Shyam Sundar, Suman Rijal, Md Abul Faiz, Marleen Boelaert
Published 2010-09-01

Five-year field results and long-term effectiveness of 20 mg/kg liposomal amphotericin B (Ambisome) for visceral leishmaniasis in Bihar, India.

by Sakib Burza, Prabhat K Sinha, Raman Mahajan, María Angeles Lima, Gaurab Mitra, Neena Verma, Manica Balasegaram, Pradeep Das
Published 2014-01-01

Risk factors for visceral leishmaniasis relapse in immunocompetent patients following treatment with 20 mg/kg liposomal amphotericin B (Ambisome) in Bihar, India.

by Sakib Burza, Prabhat K Sinha, Raman Mahajan, María Angeles Lima, Gaurab Mitra, Neena Verma, Manica Balasegaram, Pradeep Das
Published 2014-01-01

An open source pharma roadmap.

by Manica Balasegaram, Peter Kolb, John McKew, Jaykumar Menon, Piero Olliaro, Tomasz Sablinski, Zakir Thomas, Matthew H Todd, Els Torreele, John Wilbanks
Published 2017-04-01

A global biomedical R&D fund and mechanism for innovations of public health importance.

by Manica Balasegaram, Christian Bréchot, Jeremy Farrar, David Heymann, Nirmal Ganguly, Martin Khor, Yves Lévy, Precious Matsoso, Ren Minghui, Bernard Pécoul, Liu Peilong, Marcel Tanner, John-Arne Røttingen
Published 2015-05-01

Paromomycin for the treatment of visceral leishmaniasis in Sudan: a randomized, open-label, dose-finding study.

by Ahmed M Musa, Brima Younis, Ahmed Fadlalla, Catherine Royce, Manica Balasegaram, Monique Wasunna, Asrat Hailu, Tansy Edwards, Raymond Omollo, Mahmoud Mudawi, Gilbert Kokwaro, Ahmed El-Hassan, Eltahir Khalil
Published 2010-10-01

Validation of two rapid diagnostic tests for visceral leishmaniasis in Kenya.

by Jane Mbui, Monique Wasunna, Manica Balasegaram, Adrian Laussermayer, Rashid Juma, Simon Njoroge Njenga, George Kirigi, Mark Riongoita, Roberto de la Tour, Joke van Peteghem, Raymond Omollo, François Chappuis
Published 2013-01-01

Safety and efficacy of short course combination regimens with AmBisome, miltefosine and paromomycin for the treatment of visceral leishmaniasis (VL) in Bangladesh.

by Ridwanur Rahman, Vishal Goyal, Rashidul Haque, Kazi Jamil, Abul Faiz, Rasheda Samad, Sally Ellis, Manica Balasegaram, Margriet den Boer, Suman Rijal, Nathalie Strub-Wourgaft, Fabiana Alves, Jorge Alvar, Bhawna Sharma
Published 2017-05-01

Field safety and effectiveness of new visceral leishmaniasis treatment regimens within public health facilities in Bihar, India.

by Vishal Goyal, Raman Mahajan, Krishna Pandey, Shambhu Nath Singh, Ravi Shankar Singh, Nathalie Strub-Wourgaft, Fabiana Alves, Vidya Nand Rabi Das, Roshan Kamal Topno, Bhawna Sharma, Manica Balasegaram, Caryn Bern, Allen Hightower, Suman Rijal, Sally Ellis, Temmy Sunyoto, Sakib Burza, Nines Lima, Pradeep Das, Jorge Alvar
Published 2018-10-01

Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines.

by Emilie Alirol, Teodora E Wi, Manju Bala, Maria Luiza Bazzo, Xiang-Sheng Chen, Carolyn Deal, Jo-Anne R Dillon, Ranmini Kularatne, Jutta Heim, Rob Hooft van Huijsduijnen, Edward W Hook, Monica M Lahra, David A Lewis, Francis Ndowa, William M Shafer, Liz Tayler, Kimberly Workowski, Magnus Unemo, Manica Balasegaram
Published 2017-07-01

Safety and efficacy of single dose versus multiple doses of AmBisome for treatment of visceral leishmaniasis in eastern Africa: a randomised trial.

by Eltahir A G Khalil, Teklu Weldegebreal, Brima M Younis, Raymond Omollo, Ahmed M Musa, Workagegnehu Hailu, Abuzaid A Abuzaid, Thomas P C Dorlo, Zewdu Hurissa, Sisay Yifru, William Haleke, Peter G Smith, Sally Ellis, Manica Balasegaram, Ahmed M EL-Hassan, Gerard J Schoone, Monique Wasunna, Robert Kimutai, Tansy Edwards, Asrat Hailu
Published 2014-01-01

Efficacy and Safety of AmBisome in Combination with Sodium Stibogluconate or Miltefosine and Miltefosine Monotherapy for African Visceral Leishmaniasis: Phase II Randomized Trial.

by Monique Wasunna, Simon Njenga, Manica Balasegaram, Neal Alexander, Raymond Omollo, Tansy Edwards, Thomas P C Dorlo, Brima Musa, Mohammed Hassan Sharaf Ali, Mohammed Yasein Elamin, George Kirigi, Rashid Juma, Anke E Kip, Gerard J Schoone, Asrat Hailu, Joseph Olobo, Sally Ellis, Robert Kimutai, Susan Wells, Eltahir Awad Gasim Khalil, Nathalie Strub Wourgaft, Fabiana Alves, Ahmed Musa
Published 2016-09-01

Translational Research for Tuberculosis Elimination: Priorities, Challenges, and Actions.

by Christian Lienhardt, Knut Lönnroth, Dick Menzies, Manica Balasegaram, Jeremiah Chakaya, Frank Cobelens, Jennifer Cohn, Claudia M Denkinger, Thomas G Evans, Gunilla Källenius, Gilla Kaplan, Ajay M V Kumar, Line Matthiessen, Charles S Mgone, Valerie Mizrahi, Ya-Diul Mukadi, Viet Nhung Nguyen, Anders Nordström, Christine F Sizemore, Melvin Spigelman, S Bertel Squire, Soumya Swaminathan, Paul D Van Helden, Alimuddin Zumla, Karin Weyer, Diana Weil, Mario Raviglione
Published 2016-03-01

Sodium stibogluconate (SSG) & paromomycin combination compared to SSG for visceral leishmaniasis in East Africa: a randomised controlled trial.

by Ahmed Musa, Eltahir Khalil, Asrat Hailu, Joseph Olobo, Manica Balasegaram, Raymond Omollo, Tansy Edwards, Juma Rashid, Jane Mbui, Brima Musa, Abuzaid Abdalla Abuzaid, Osama Ahmed, Ahmed Fadlalla, Ahmed El-Hassan, Marius Mueller, Geoffrey Mucee, Simon Njoroge, Veronica Manduku, Geoffrey Mutuma, Lilian Apadet, Hudson Lodenyo, Dedan Mutea, George Kirigi, Sisay Yifru, Getahun Mengistu, Zewdu Hurissa, Workagegnehu Hailu, Teklu Weldegebreal, Hailemariam Tafes, Yalemtsehay Mekonnen, Eyasu Makonnen, Serah Ndegwa, Patrick Sagaki, Robert Kimutai, Josephine Kesusu, Rhoda Owiti, Sally Ellis, Monique Wasunna
Published 2012-01-01

Geographical variation in the response of visceral leishmaniasis to paromomycin in East Africa: a multicentre, open-label, randomized trial.

by Asrat Hailu, Ahmed Musa, Monique Wasunna, Manica Balasegaram, Sisay Yifru, Getahun Mengistu, Zewdu Hurissa, Workagegnehu Hailu, Teklu Weldegebreal, Samson Tesfaye, Eyasu Makonnen, Eltahir Khalil, Osama Ahmed, Ahmed Fadlalla, Ahmed El-Hassan, Muzamil Raheem, Marius Mueller, Yousif Koummuki, Juma Rashid, Jane Mbui, Geoffrey Mucee, Simon Njoroge, Veronica Manduku, Alice Musibi, Geoffrey Mutuma, Fredrick Kirui, Hudson Lodenyo, Dedan Mutea, George Kirigi, Tansy Edwards, Peter Smith, Lawrence Muthami, Catherine Royce, Sally Ellis, Moses Alobo, Raymond Omollo, Josephine Kesusu, Rhoda Owiti, John Kinuthia, Leishmaniasis East Africa Platform (LEAP) group
Published 2010-10-01