Contribution of CYP2D6 Functional Activity to Oxycodone Efficacy in Pain Management: Genetic Polymorphisms, Phenoconversion, and Tissue-Selective Metabolism

by Malavika Deodhar, Jacques Turgeon, Veronique Michaud
Published 2021-09-01

Chronic Inflammatory Status Observed in Patients with Type 2 Diabetes Induces Modulation of Cytochrome P450 Expression and Activity

by Lucy Darakjian, Malavika Deodhar, Jacques Turgeon, Veronique Michaud
Published 2021-05-01

Assessing the Mechanism of Fluoxetine-Mediated CYP2D6 Inhibition

by Malavika Deodhar, Sweilem B. Al Rihani, Lucy Darakjian, Jacques Turgeon, Veronique Michaud
Published 2021-01-01

ACE2 as a Therapeutic Target for COVID-19; its Role in Infectious Processes and Regulation by Modulators of the RAAS System

by Veronique Michaud, Malavika Deodhar, Meghan Arwood, Sweilem B Al Rihani, Pamela Dow, Jacques Turgeon
Published 2020-07-01

Disease-Induced Modulation of Drug Transporters at the Blood–Brain Barrier Level

by Sweilem B. Al Rihani, Lucy I. Darakjian, Malavika Deodhar, Pamela Dow, Jacques Turgeon, Veronique Michaud
Published 2021-04-01

Risk Assessment of Drug‐Induced Long QT Syndrome for Some COVID‐19 Repurposed Drugs

by Veronique Michaud, Pamela Dow, Sweilem B. Al Rihani, Malavika Deodhar, Meghan Arwood, Brian Cicali, Jacques Turgeon
Published 2021-01-01

Risk of Adverse Drug Events Following the Virtual Addition of COVID-19 Repurposed Drugs to Drug Regimens of Frail Older Adults with Polypharmacy

by Sweilem B. Al Rihani, Matt K. Smith, Ravil Bikmetov, Malavika Deodhar, Pamela Dow, Jacques Turgeon, Veronique Michaud
Published 2020-08-01

Mechanisms of CYP450 Inhibition: Understanding Drug-Drug Interactions Due to Mechanism-Based Inhibition in Clinical Practice

by Malavika Deodhar, Sweilem B Al Rihani, Meghan J. Arwood, Lucy Darakjian, Pamela Dow, Jacques Turgeon, Veronique Michaud
Published 2020-09-01