Folate Deficiency Triggers the Abnormal Segregation of a Region With Large Cluster of CG-Rich Trinucleotide Repeats on Human Chromosome 2

by Lorenza Garribba, Ivan Vogel, Mads Lerdrup, Marisa M. Gonçalves Dinis, Liqun Ren, Ying Liu
Published 2021-07-01

REST-mediated recruitment of polycomb repressor complexes in mammalian cells.

by Nikolaj Dietrich, Mads Lerdrup, Eskild Landt, Shuchi Agrawal-Singh, Mads Bak, Niels Tommerup, Juri Rappsilber, Erik Södersten, Klaus Hansen
Published 2012-01-01

Dopamine signaling leads to loss of Polycomb repression and aberrant gene activation in experimental parkinsonism.

by Erik Södersten, Michael Feyder, Mads Lerdrup, Ana-Luisa Gomes, Hanna Kryh, Giada Spigolon, Jocelyne Caboche, Gilberto Fisone, Klaus Hansen
Published 2014-09-01

PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells

by Shuchi Agrawal Singh, Mads Lerdrup, Ana-Luisa R Gomes, Harmen JG van de Werken, Jens Vilstrup Johansen, Robin Andersson, Albin Sandelin, Kristian Helin, Klaus Hansen
Published 2019-01-01

Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing

by Muhammad Shoaib, David Walter, Peter J. Gillespie, Fanny Izard, Birthe Fahrenkrog, David Lleres, Mads Lerdrup, Jens Vilstrup Johansen, Klaus Hansen, Eric Julien, J. Julian Blow, Claus S. Sørensen
Published 2018-09-01

Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes

by Muhammad Shoaib, Qinming Chen, Xiangyan Shi, Nidhi Nair, Chinmayi Prasanna, Renliang Yang, David Walter, Klaus S. Frederiksen, Hjorleifur Einarsson, J. Peter Svensson, Chuan Fa Liu, Karl Ekwall, Mads Lerdrup, Lars Nordenskiöld, Claus S. Sørensen
Published 2021-08-01