The Neglected Insulin: IGF-II, a Metabolic Regulator with Implications for Diabetes, Obesity, and Cancer

by Jeff M. P. Holly, Kalina Biernacka, Claire M. Perks
Published 2019-10-01

Systemic Metabolism, Its Regulators, and Cancer: Past Mistakes and Future Potential

by Jeff M. P. Holly, Kalina Biernacka, Claire M. Perks
Published 2019-02-01

Intrinsic, pro-apoptotic effects of IGFBP-3 on breast cancer cells are reversible: Involvement of PKA, Rho and ceramide.

by Claire M Perks, Carla eBurrows, Jeff M P Holly
Published 2011-05-01

Obesity, Diabetes and COVID-19: An Infectious Disease Spreading From the East Collides With the Consequences of an Unhealthy Western Lifestyle

by Jeff M. P. Holly, Kalina Biernacka, Nick Maskell, Claire M. Perks
Published 2020-09-01

Glucose Concentration in Cell Culture Medium Influences the BRCA1-Mediated Regulation of the Lipogenic Action of IGF-I in Breast Cancer Cells

by Moses O. Koobotse, Dayane Schmidt, Jeff M. P. Holly, Claire M. Perks
Published 2020-11-01

Advances on inorganic scintillator-based optic fiber dosimeters

by Liang Ding, Qiong Wu, Qun Wang, Yamei Li, Richard M. Perks, Liang Zhao
Published 2020-10-01

Hyperglycemia Promotes TMPRSS2-ERG Gene Fusion in Prostate Cancer Cells via Upregulating Insulin-Like Growth Factor-Binding Protein-2

by Jeff M. P. Holly, Jessica Broadhurst, Rehanna Mansor, Amit Bahl, Claire M. Perks
Published 2017-11-01

Effects of clear-fell harvesting on soil CO₂, CH₄, and N₂O fluxes in an upland Sitka spruce stand in England

by S. Yamulki, J. Forster, G. Xenakis, A. Ash, J. Brunt, M. Perks, J. I. L. Morison
Published 2021-07-01

Glioma Stem-Like Cells and Metabolism: Potential for Novel Therapeutic Strategies

by Abigail Harland, Xia Liu, Mattia Ghirardello, M. Carmen Galan, Claire M. Perks, Kathreena M. Kurian
Published 2021-08-01

Mini Review: Opposing Pathologies in Cancer and Alzheimer's Disease: Does the PI3K/Akt Pathway Provide Clues?

by Rachel M. Barker, Jeff M. P. Holly, Kalina M. Biernacka, Shelley J. Allen-Birt, Claire M. Perks
Published 2020-06-01

Interaction between GRP78 and IGFBP-3 Affects Tumourigenesis and Prognosis in Breast Cancer Patients

by Hanna A. Zielinska, Carl S. Daly, Ahmad Alghamdi, Amit Bahl, Muhammed Sohail, Paul White, Sarah R. Dean, Jeff M. P. Holly, Claire M. Perks
Published 2020-12-01

CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer

by Simon Uzor, Sean R. Porazinski, Ling Li, Bethany Clark, Masahiko Ajiro, Kei Iida, Masatoshi Hagiwara, Abdullah A. Alqasem, Claire M. Perks, Ian D. Wilson, Sebastian Oltean, Michael R. Ladomery
Published 2021-04-01

Alteration of Metabolic Conditions Impacts the Regulation of IGF-II/H19 Imprinting Status in Prostate Cancer

by Georgina Kingshott, Kalina Biernacka, Alex Sewell, Paida Gwiti, Rachel Barker, Hanna Zielinska, Amanda Gilkes, Kathryn McCarthy, Richard M. Martin, J. Athene Lane, Lucy McGeagh, Anthony Koupparis, Edward Rowe, Jon Oxley, Jeff M. P. Holly, Claire M. Perks
Published 2021-02-01