Therapeutic melanoma vaccine with cancer stem cell phenotype represses exhaustion and maintains antigen-specific T cell stemness by up-regulating BCL6

by Patrycja Czerwinska, Marcin Rucinski, Nikola Wlodarczyk, Anna Jaworska, Iga Grzadzielewska, Katarzyna Gryska, Lukasz Galus, Jacek Mackiewicz, Andrzej Mackiewicz
Published 2020-01-01

The Analysis of Inflammation-Related Proteins in a Cargo of Exosomes Derived from the Serum of Uveal Melanoma Patients Reveals Potential Biomarkers of Disease Progression

by Joanna Patrycja Wróblewska, Michał Stefan Lach, Katarzyna Kulcenty, Łukasz Galus, Wiktoria Maria Suchorska, Daniel Rösel, Jan Brábek, Andrzej Marszałek
Published 2021-07-01

Functional T Cell Reactivity to Melanocyte Antigens Is Lost during the Progression of Malignant Melanoma, but Is Restored by Immunization

by Anna Przybyla, Alexander A. Lehmann, Ting Zhang, Jacek Mackiewicz, Łukasz Galus, Greg A. Kirchenbaum, Andrzej Mackiewicz, Paul V. Lehmann
Published 2021-01-01

Whole cell melanoma vaccine genetically modified to stem cells like phenotype generates specific immune responses to ALDH1A1 and long-term survival in advanced melanoma patients

by Eliza Kwiatkowska-Borowczyk, Patrycja Czerwińska, Jacek Mackiewicz, Katarzyna Gryska, Urszula Kazimierczak, Katarzyna Tomela, Anna Przybyła, Anna Karolina Kozłowska, Łukasz Galus, Łukasz Kwinta, Ewelina Dondajewska, Agnieszka Gąbka-Buszek, Monika Żakowska, Andrzej Mackiewicz
Published 2018-11-01