Hypoxia and Chromatin: A Focus on Transcriptional Repression Mechanisms

by Michael Batie, Luis del Peso, Sonia Rocha
Published 2018-04-01

Hypoxia negatively regulates antimetastatic PEDF in melanoma cells by a hypoxia inducible factor-independent, autophagy dependent mechanism.

by Asunción Fernández-Barral, José Luis Orgaz, Valentí Gomez, Luis del Peso, María José Calzada, Benilde Jiménez
Published 2012-01-01

Comparative Study of Organoids from Patient-Derived Normal and Tumor Colon and Rectal Tissue

by Alba Costales-Carrera, Asunción Fernández-Barral, Pilar Bustamante-Madrid, Orlando Domínguez, Laura Guerra-Pastrián, Ramón Cantero, Luis del Peso, Aurora Burgos, Antonio Barbáchano, Alberto Muñoz
Published 2020-08-01

miR-127 protects proximal tubule cells against ischemia/reperfusion: identification of kinesin family member 3B as miR-127 target.

by Elia Aguado-Fraile, Edurne Ramos, David Sáenz-Morales, Elisa Conde, Ignacio Blanco-Sánchez, Konstantinos Stamatakis, Luis del Peso, Edwin Cuppen, Bernhard Brüne, María Laura García Bermejo
Published 2012-01-01

Cooperativity of stress-responsive transcription factors in core hypoxia-inducible factor binding regions.

by Diego Villar, Amaya Ortiz-Barahona, Laura Gómez-Maldonado, Nuria Pescador, Fátima Sánchez-Cabo, Hubert Hackl, Benjamin A T Rodriguez, Zlatko Trajanoski, Ana Dopazo, Tim H M Huang, Pearlly S Yan, Luis Del Peso
Published 2012-01-01

Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1.

by Nuria Pescador, Diego Villar, Daniel Cifuentes, Mar Garcia-Rocha, Amaya Ortiz-Barahona, Silvia Vazquez, Angel Ordoñez, Yolanda Cuevas, David Saez-Morales, Maria Laura Garcia-Bermejo, Manuel O Landazuri, Joan Guinovart, Luis del Peso
Published 2010-03-01

Regulatory and Functional Connection of Microphthalmia-Associated Transcription Factor and Anti-Metastatic Pigment Epithelium Derived Factor in Melanoma

by Asunción Fernández-Barral, Jose Luis Orgaz, Pablo Baquero, Zaheer Ali, Alberto Moreno, María Tiana, Valentí Gómez, Erica Riveiro-Falkenbach, Carmen Cañadas, Sandra Zazo, Corine Bertolotto, Irwin Davidson, Jose Luis Rodríguez-Peralto, Ignacio Palmero, Federico Rojo, Lasse Dahl Jensen, Luis del Peso, Benilde Jiménez
Published 2014-06-01

Hypoxia inducible factor 1-alpha (HIF-1 alpha) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survival.

by Elisa Conde, Laura Alegre, Ignacio Blanco-Sánchez, David Sáenz-Morales, Elia Aguado-Fraile, Belén Ponte, Edurne Ramos, Ana Sáiz, Carlos Jiménez, Angel Ordoñez, Manuel López-Cabrera, Luis del Peso, Manuel O de Landázuri, Fernando Liaño, Rafael Selgas, Jose Antonio Sanchez-Tomero, María Laura García-Bermejo
Published 2012-01-01

ERK2, but not ERK1, mediates acquired and "de novo" resistance to imatinib mesylate: implication for CML therapy.

by Clara I Aceves-Luquero, Anupriya Agarwal, Juan L Callejas-Valera, Laura Arias-González, Azucena Esparís-Ogando, Luis del Peso Ovalle, Itxaso Bellón-Echeverria, Miguel A de la Cruz-Morcillo, Eva M Galán Moya, Inmaculada Moreno Gimeno, Juan C Gómez, Michael W Deininger, Atanasio Pandiella, Ricardo Sánchez Prieto
Published 2009-07-01

ERK5/BMK1 Is a Novel Target of the Tumor Suppressor VHL: Implication in Clear Cell Renal Carcinoma

by Laura Arias-González, Inmaculada Moreno-Gimeno, Antonio Rubio del Campo, Serrano-Oviedo Leticia, María Llanos Valero, Azucena Esparís-Ogando, Miguel Ángel de la Cruz-Morcillo, Pedro Melgar-Rojas, Jesús García-Cano, Francisco José Cimas, María José Ruiz Hidalgo, Alfonso Prado, Juan Luis Callejas-Valera, Syong Hyun Nam-Cha, José Miguel Giménez-Bachs, Antonio S Salinas-Sánchez, Atanasio Pandiella, Luis del Peso, Ricardo Sánchez Prieto
Published 2013-06-01