Adverse Events of Prostacyclin Mimetics in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis

by Christina Picken, Konstantinos C. Fragkos, Mohammad Eddama, Gerry Coghlan, Lucie H. Clapp
Published 2019-04-01

The Prostacyclin Analogue, Treprostinil, Used in the Treatment of Pulmonary Arterial Hypertension, is a Potent Antagonist of TREK-1 and TREK-2 Potassium Channels

by Kevin P. Cunningham, Kevin P. Cunningham, Lucie H. Clapp, Alistair Mathie, Alistair Mathie, Emma L. Veale
Published 2021-06-01

Prostanoid EP2 Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells

by Jigisha A. Patel, Lei Shen, Susan M. Hall, Chabha Benyahia, Xavier Norel, Robin J. McAnulty, Shahin Moledina, Adam M. Silverstein, Brendan J. Whittle, Lucie H. Clapp
Published 2018-08-01