A Biophysical Approach to the Identification of Novel ApoE Chemical Probes

by Lucas Kraft, Louise C. Serpell, John R. Atack
Published 2019-01-01

Nuclear Tau and Its Potential Role in Alzheimer’s Disease

by Mahmoud Bukar Maina, Youssra K. Al-Hilaly, Louise C. Serpell
Published 2016-01-01

The Involvement of Aβ42 and Tau in Nucleolar and Protein Synthesis Machinery Dysfunction

by Mahmoud B. Maina, Mahmoud B. Maina, Laura J. Bailey, Aidan J. Doherty, Louise C. Serpell
Published 2018-08-01

Metal- and UV- Catalyzed Oxidation Results in Trapped Amyloid-β Intermediates Revealing that Self-Assembly Is Required for Aβ-Induced Cytotoxicity

by Mahmoud B. Maina, Gunasekhar Burra, Youssra K. Al-Hilaly, Kurtis Mengham, Kate Fennell, Louise C. Serpell
Published 2020-10-01

An evaluation of the self-assembly enhancing properties of cell-derived hexameric amyloid-β

by Devkee M. Vadukul, Céline Vrancx, Pierre Burguet, Sabrina Contino, Nuria Suelves, Louise C. Serpell, Loïc Quinton, Pascal Kienlen-Campard
Published 2021-06-01

Oxidative Stress Conditions Result in Trapping of PHF-Core Tau (297–391) Intermediates

by Mahmoud B. Maina, Youssra K. Al-Hilaly, Gunasekhar Burra, Janet E. Rickard, Charles R. Harrington, Claude M. Wischik, Louise C. Serpell
Published 2021-03-01

Polyglutamine aggregate structure in vitro and in vivo; new avenues for coherent anti-Stokes Raman scattering microscopy.

by Nicolas M Perney, Lucy Braddick, Martin Jurna, Erik T Garbacik, Herman L Offerhaus, Louise C Serpell, Ewan Blanch, Lindy Holden-Dye, William S Brocklesby, Tracy Melvin
Published 2012-01-01

The involvement of tau in nucleolar transcription and the stress response

by Mahmoud B. Maina, Laura J. Bailey, Sherin Wagih, Luca Biasetti, Saskia J. Pollack, James P. Quinn, Julian R. Thorpe, Aidan J. Doherty, Louise C. Serpell
Published 2018-07-01

Transition of Nano-Architectures Through Self-Assembly of Lipidated β3-Tripeptide Foldamers

by Nathan Habila, Ketav Kulkarni, Tzong-Hsien Lee, Zahraa S. Al-Garawi, Zahraa S. Al-Garawi, Louise C. Serpell, Marie-Isabel Aguilar, Mark P. Del Borgo, Mark P. Del Borgo
Published 2020-03-01

Tau Filament Self-Assembly and Structure: Tau as a Therapeutic Target

by Sebastian S. Oakley, Mahmoud B. Maina, Mahmoud B. Maina, Karen E. Marshall, Youssra K. Al-Hilaly, Youssra K. Al-Hilaly, Charlie R. Harrington, Charlie R. Harrington, Claude M. Wischik, Claude M. Wischik, Louise C. Serpell
Published 2020-11-01

MIRRAGGE – Minimum Information Required for Reproducible AGGregation Experiments

by Pedro M. Martins, Pedro M. Martins, Susanna Navarro, Alexandra Silva, Maria F. Pinto, Zsuzsa Sárkány, Francisco Figueiredo, Francisco Figueiredo, Francisco Figueiredo, Pedro José Barbosa Pereira, Francisca Pinheiro, Zuzana Bednarikova, Michał Burdukiewicz, Oxana V. Galzitskaya, Oxana V. Galzitskaya, Zuzana Gazova, Cláudio M. Gomes, Annalisa Pastore, Louise C. Serpell, Rostislav Skrabana, Rostislav Skrabana, Vytautas Smirnovas, Mantas Ziaunys, Daniel E. Otzen, Salvador Ventura, Sandra Macedo-Ribeiro
Published 2020-11-01