Intestinal and systemic inflammation induced by symptomatic and asymptomatic enterotoxigenic E. coli infection and impact on intestinal colonization and ETEC specific immune respon...

by Jessica Brubaker, Xueyan Zhang, A. Louis Bourgeois, Clayton Harro, David A Sack, Subhra Chakraborty
Published 2021-01-01

Estimating diarrheal illness and deaths attributable to Shigellae and enterotoxigenic Escherichia coli among older children, adolescents, and adults in South Asia and Africa.

by Laura M Lamberti, A Louis Bourgeois, Christa L Fischer Walker, Robert E Black, David Sack
Published 2014-02-01

Enterotoxigenic Escherichia coli Multilocus Sequence Types in Guatemala and Mexico

by Matilda Nicklasson, John D. Klena, Claudia Rodas, August Louis Bourgeois, Olga Torres, Ann-Mari Svennerholm, Åsa Sjöling
Published 2010-01-01

Vaccines for Protecting Infants from Bacterial Causes of Diarrheal Disease

by Richard Walker, Robert W. Kaminski, Chad Porter, Robert K. M. Choy, Jessica A. White, James M. Fleckenstein, Fred Cassels, Louis Bourgeois
Published 2021-06-01

<i>Shigella</i> -Specific Immune Profiles Induced after Parenteral Immunization or Oral Challenge with Either Shigella flexneri 2a or Shigella sonnei

by Kristen A. Clarkson, Chad K. Porter, Kawsar R. Talaat, Robert W. Frenck, Cristina Alaimo, Patricia Martin, A. Louis Bourgeois, Robert W. Kaminski
Published 2021-08-01

Evaluation of the reactogenicity, adjuvanticity and antigenicity of LT(R192G) and LT(R192G/L211A) by intradermal immunization in mice.

by Milton Maciel, Mark Smith, Steven T Poole, Renee M Laird, Julianne E Rollenhagen, Robert W Kaminski, Heather Wenzel, A Louis Bourgeois, Stephen J Savarino
Published 2019-01-01

Linking inherent O-Linked Protein Glycosylation of YghJ to Increased Antigen Potential

by Mette Thorsing, Thøger Jensen Krogh, Lars Vitved, Arkadiusz Nawrocki, Rikke Jakobsen, Martin R. Larsen, Subhra Chakraborty, A. Louis Bourgeois, Ann Zahle Andersen, Anders Boysen
Published 2021-08-01

Impact of lower challenge doses of enterotoxigenic Escherichia coli on clinical outcome, intestinal colonization and immune responses in adult volunteers.

by Subhra Chakraborty, Clayton Harro, Barbara DeNearing, Jessica Brubaker, Sean Connor, Nicole Maier, Len Dally, Jorge Flores, A Louis Bourgeois, Richard Walker, David A Sack
Published 2018-04-01

Clinical endpoints in the controlled human challenge model for Shigella: A call for standardization and the development of a disease severity score.

by Chad K Porter, Amanda Lynen, Mark S Riddle, Kawsar Talaat, David Sack, Ramiro L Gutiérrez, Robin McKenzie, Barbara DeNearing, Brittany Feijoo, Robert W Kaminski, David N Taylor, Beth D Kirkpatrick, A Louis Bourgeois
Published 2018-01-01

An Evidenced-Based Scale of Disease Severity following Human Challenge with Enteroxigenic Escherichia coli.

by Chad K Porter, Mark S Riddle, Ashley N Alcala, David A Sack, Clayton Harro, Subhra Chakraborty, Ramiro L Gutierrez, Stephen J Savarino, Michael Darsley, Robin McKenzie, Barbara DeNearing, Hans Steinsland, David R Tribble, A Louis Bourgeois
Published 2016-01-01

Refinement of the CS6-expressing enterotoxigenic Escherichia coli strain B7A human challenge model: A randomized trial.

by Kawsar R Talaat, Chad K Porter, Kayla M Jaep, Christopher A Duplessis, Ramiro L Gutierrez, Milton Maciel, Brittany Adjoodani, Brittany Feijoo, Subhra Chakraborty, Jessica Brubaker, Stefanie A Trop, Mark S Riddle, Sabrina S Joseph, A Louis Bourgeois, Michael G Prouty
Published 2020-01-01

Immune response characterization in a human challenge study with a Shigella flexneri 2a bioconjugate vaccine

by Kristen A. Clarkson, Kawsar R. Talaat, Cristina Alaimo, Patricia Martin, A. Louis Bourgeois, Anita Dreyer, Chad K. Porter, Subhra Chakraborty, Jessica Brubaker, Daniel Elwood, Rahel Frölich, Barbara DeNearing, Hailey P. Weerts, Brittany Feijoo, Jane Halpern, David Sack, Mark S. Riddle, Veronica Gambillara Fonck, Robert W. Kaminski
Published 2021-04-01

Human challenge study with a Shigella bioconjugate vaccine: Analyses of clinical efficacy and correlate of protection

by Kawsar R. Talaat, Cristina Alaimo, Patricia Martin, A. Louis Bourgeois, Anita M. Dreyer, Robert W. Kaminski, Chad K. Porter, Subhra Chakraborty, Kristen A. Clarkson, Jessica Brubaker, Daniel Elwood, Rahel Frölich, Barbara DeNearing, Hailey Weerts, Brittany L. Feijoo, Jane Halpern, David Sack, Mark S. Riddle, Veronica Gambillara Fonck
Published 2021-04-01