Approximating multivariate posterior distribution functions from Monte Carlo samples for sequential Bayesian inference.

by Bram Thijssen, Lodewyk F A Wessels
Published 2020-01-01

Molecular characterization of breast and lung tumors by integration of multiple data types with functional sparse-factor analysis.

by Tycho Bismeijer, Sander Canisius, Lodewyk F A Wessels
Published 2018-10-01

Genomic data integration by WON-PARAFAC identifies interpretable factors for predicting drug-sensitivity in vivo

by Yongsoo Kim, Tycho Bismeijer, Wilbert Zwart, Lodewyk F. A. Wessels, Daniel J. Vis
Published 2019-11-01

RUNX2/CBFB modulates the response to MEK inhibitors through activation of receptor tyrosine kinases in KRAS-mutant colorectal cancer

by Tonći Šuštić, Evert Bosdriesz, Sake van Wageningen, Lodewyk F.A. Wessels, René Bernards
Published 2020-02-01

Module-based outcome prediction using breast cancer compendia.

by Martin H van Vliet, Christiaan N Klijn, Lodewyk F A Wessels, Marcel J T Reinders
Published 2007-01-01

RUBIC identifies driver genes by detecting recurrent DNA copy number breaks

by Ewald van Dyk, Marlous Hoogstraat, Jelle ten Hoeve, Marcel J. T. Reinders, Lodewyk F. A. Wessels
Published 2016-07-01

Breast cancer subtype specific classifiers of response to neoadjuvant chemotherapy do not outperform classifiers trained on all subtypes.

by Jorma J de Ronde, Marc Jan Bonder, Esther H Lips, Sjoerd Rodenhuis, Lodewyk F A Wessels
Published 2014-01-01

A critical evaluation of network and pathway-based classifiers for outcome prediction in breast cancer.

by Christine Staiger, Sidney Cadot, Raul Kooter, Marcus Dittrich, Tobias Müller, Gunnar W Klau, Lodewyk F A Wessels
Published 2012-01-01

Integration of clinical and gene expression data has a synergetic effect on predicting breast cancer outcome.

by Martin H van Vliet, Hugo M Horlings, Marc J van de Vijver, Marcel J T Reinders, Lodewyk F A Wessels
Published 2012-01-01

Multiplexed Cas9 targeting reveals genomic location effects and gRNA-based staggered breaks influencing mutation efficiency

by Santiago Gisler, Joana P. Gonçalves, Waseem Akhtar, Johann de Jong, Alexey V. Pindyurin, Lodewyk F. A. Wessels, Maarten van Lohuizen
Published 2019-04-01

Identification of a Druggable Pathway Controlling Glioblastoma Invasiveness

by Nora Pencheva, Mark C. de Gooijer, Daniel J. Vis, Lodewyk F.A. Wessels, Tom Würdinger, Olaf van Tellingen, René Bernards
Published 2017-07-01

Androgen receptor DNA binding and chromatin accessibility profiling in prostate cancer

by Ekaterina Nevedomskaya, Suzan Stelloo, Henk G. van der Poel, Jeroen de Jong, Lodewyk F.A. Wessels, Andries M. Bergman, Wilbert Zwart
Published 2016-03-01

Lack of genomic heterogeneity at high-resolution aCGH between primary breast cancers and their paired lymph node metastases.

by Marieke A Vollebergh, Christiaan Klijn, Philip C Schouten, Jelle Wesseling, Danielle Israeli, Bauke Ylstra, Lodewyk F A Wessels, Jos Jonkers, Sabine C Linn
Published 2014-01-01

Gene expression profiles from formalin fixed paraffin embedded breast cancer tissue are largely comparable to fresh frozen matched tissue.

by Lorenza Mittempergher, Jorma J de Ronde, Marja Nieuwland, Ron M Kerkhoven, Iris Simon, Emiel J Th Rutgers, Lodewyk F A Wessels, Laura J Van't Veer
Published 2011-01-01

Correction to: A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers

by Tonći Šuštić, Sake van Wageningen, Evert Bosdriesz, Robert J. D. Reid, John Dittmar, Cor Lieftink, Roderick L. Beijersbergen, Lodewyk F. A. Wessels, Rodney Rothstein, René Bernards
Published 2021-02-01

A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers

by Tonći Šuštić, Sake van Wageningen, Evert Bosdriesz, Robert J. D. Reid, John Dittmar, Cor Lieftink, Roderick L. Beijersbergen, Lodewyk F. A. Wessels, Rodney Rothstein, René Bernards
Published 2018-11-01

Chromatin landscapes of retroviral and transposon integration profiles.

by Johann de Jong, Waseem Akhtar, Jitendra Badhai, Alistair G Rust, Roland Rad, John Hilkens, Anton Berns, Maarten van Lohuizen, Lodewyk F A Wessels, Jeroen de Ridder
Published 2014-04-01

Ubiquitin E3 ligase Ring1b/Rnf2 of polycomb repressive complex 1 contributes to stable maintenance of mouse embryonic stem cells.

by Petra van der Stoop, Erwin A Boutsma, Danielle Hulsman, Sonja Noback, Mike Heimerikx, Ron M Kerkhoven, J Willem Voncken, Lodewyk F A Wessels, Maarten van Lohuizen
Published 2008-05-01

Role of variant allele fraction and rare SNP filtering to improve cellular DNA repair endpoint association.

by David M Vossen, Caroline V M Verhagen, Reidar Grénman, Roelof J C Kluin, Marcel Verheij, Michiel W M van den Brekel, Lodewyk F A Wessels, Conchita Vens
Published 2018-01-01

Genetic Factors Associated with a Poor Outcome in Head and Neck Cancer Patients Receiving Definitive Chemoradiotherapy

by David M. Vossen, Caroline V.M. Verhagen, Martijn van der Heijden, Paul B.M. Essers, Harry Bartelink, Marcel Verheij, Lodewyk F.A. Wessels, Michiel W.M. van den Brekel, Conchita Vens
Published 2019-03-01